AutismKB 2.0

Annotation Details for UBE2E2


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Basic Information Top
Gene Symbol:UBE2E2 ( FLJ25157,UBCH8 )
Gene Full Name: ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
Band: 3p24.3
Quick LinksEntrez ID:7325; OMIM: 602163; Uniprot ID:UB2E2_HUMAN; ENSEMBL ID: ENSG00000182247; HGNC ID: 12478
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
No data
GO ID Evidence Qualifier GO_term References
GO:0004842IDA-ubiquitin-protein transferase activity20061386
GO:0005515IPI-protein binding19549727
GO:0005524IEA-ATP binding-
GO:0042296IDA-ISG15 transferase activity16428300
GO:0061631IDA-ubiquitin conjugating enzyme activity9371400
GO ID Evidence Qualifier GO_term References
GO:0006974IMP-cellular response to DNA damage stimulus21628527
GO:0032020IDA-ISG15-protein conjugation16428300
GO:0070534IDA-protein K63-linked ubiquitination20061386
GO:0070936IDA-protein K48-linked ubiquitination20061386
GO:0070979IDA-protein K11-linked ubiquitination20061386
GO:1900087IGI-positive regulation of G1/S transition of mitotic cell cycle21628527
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
UBE2E2XIAP10682819549727 Two-hybrid
UBE2E2XIAP11317319549727 Two-hybrid
UBE2E2TRIM2311317319549727 Two-hybrid
UBE2E2TRIM2310686819549727 Two-hybrid
UBE2E2MID111317319549727 Two-hybrid
UBE2E2MID111042719549727 Two-hybrid
UBE2E2RING111317319549727 Two-hybrid
UBE2E2RING111194719549727 Two-hybrid
UBE2E2RNF211197219549727 Two-hybrid
UBE2E2RNF211317319549727 Two-hybrid
UBE2E2RNF411197419549727 Two-hybrid
UBE2E2RNF411317319549727 Two-hybrid
UBE2E2RNF511317319549727 Two-hybrid
UBE2E2RNF511197519549727 Two-hybrid
RNF8UBE2E211449211322894 Two-hybrid
RNF8UBE2E211317311322894 Two-hybrid
RNF14UBE2E211496811322894 19549727 Two-hybrid
RNF14UBE2E211317311322894 19549727 Two-hybrid
STUB1UBE2E211556318485199 Reconstituted Complex
STUB1UBE2E211317318485199 Reconstituted Complex
ARIH2UBE2E211569419549727 Two-hybrid
ARIH2UBE2E211317319549727 Two-hybrid
MARCH3UBE2E212541619549727 Two-hybrid
MARCH3UBE2E211317319549727 Two-hybrid
RNF166UBE2E211317319549727 Two-hybrid
RNF166UBE2E212546519549727 Two-hybrid
DTX3LUBE2E211317319549727 Two-hybrid
DTX3LUBE2E212739219549727 Two-hybrid
DTX3UBE2E212820319549727 Two-hybrid
DTX3UBE2E211317319549727 Two-hybrid
UBOX5UBE2E211317319549727 Two-hybrid
UBOX5UBE2E211655419549727 Two-hybrid
TRIM2UBE2E211691019549727 Two-hybrid
TRIM2UBE2E211317319549727 Two-hybrid
RNF11UBE2E211317319549727 Two-hybrid
RNF11UBE2E211794119549727 Two-hybrid
RLIMUBE2E211931919549727 Two-hybrid
RLIMUBE2E211317319549727 Two-hybrid
RNF111UBE2E212014619549727 Two-hybrid
RNF111UBE2E211317319549727 Two-hybrid
RNF125UBE2E211317319549727 Two-hybrid
RNF125UBE2E212028119549727 Two-hybrid
CHFRUBE2E211317319549727 Two-hybrid
CHFRUBE2E212086119549727 Two-hybrid
RNF114UBE2E211317319549727 Two-hybrid
RNF114UBE2E212099119549727 Two-hybrid
TRIM39UBE2E211317319549727 Two-hybrid
TRIM39UBE2E212117019549727 Two-hybrid
RNF25UBE2E211317319549727 Two-hybrid
RNF25UBE2E212213319549727 Two-hybrid
MKRN3UBE2E211317319549727 Two-hybrid
MKRN3UBE2E211347919549727 Two-hybrid
ZNRF1UBE2E211317319549727 Two-hybrid
ZNRF1UBE2E212437119549727 Two-hybrid
RNF185UBE2E211317319549727 Two-hybrid
RNF185UBE2E212483419549727 Two-hybrid
DZIP3UBE2E211317319549727 Two-hybrid
DZIP3UBE2E211502119549727 Two-hybrid
RNF10UBE2E211317319549727 Two-hybrid
RNF10UBE2E211524919549727 Two-hybrid
PCGF2UBE2E211317319690564 Two-hybrid
PCGF2UBE2E211349719690564 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2384997
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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