AutismKB 2.0

Annotation Details for UFD1L


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Basic Information Top
Gene Symbol:UFD1L ( UFD1 )
Gene Full Name: ubiquitin fusion degradation 1 like (yeast)
Band: 22q11.21
Quick LinksEntrez ID:7353; OMIM: 601754; Uniprot ID:UFD1_HUMAN; ENSEMBL ID: ENSG00000070010; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus21630459
GO:0005654TAS-nucleoplasm-
GO:0005783IDA-endoplasmic reticulum-
GO:0005829IEA-cytosol-
GO:0034098IDA-VCP-NPL4-UFD1 AAA ATPase complex26471729
GO:0034098ISS-VCP-NPL4-UFD1 AAA ATPase complex-
GO:0036501IPI-UFD1-NPL4 complex11574150
GO ID Evidence Qualifier GO_term References
GO:0004843TAS-thiol-dependent ubiquitin-specific protease activity9063746
GO:0005102IEA-receptor binding-
GO:0005515IPI-protein binding11574150
GO:0032403IEA-protein complex binding-
GO:0036435IEA-K48-linked polyubiquitin binding-
GO:0051117IEA-ATPase binding-
GO ID Evidence Qualifier GO_term References
GO:0001501TAS-skeletal system development10024240
GO:0006511IMP-ubiquitin-dependent protein catabolic process26471729
GO:0016579TAS-protein deubiquitination-
GO:0030970IMP-retrograde protein transport, ER to cytosol25660456
GO:0032480IMP-negative regulation of type I interferon production26471729
GO:0039536IMP-negative regulation of RIG-I signaling pathway26471729
GO:0043161IEA-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0070987TAS-error-free translesion synthesis-
GO:0071712IMP-ER-associated misfolded protein catabolic process24089527
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
UFD1LAMFR11320017681147 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
UFD1LAMFR10676417681147 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
UFD1LBIRC511320016322459 Affinity Capture-Western
UFD1LBIRC510682916322459 Affinity Capture-Western
UFD1LHMOX111320018544348 Affinity Capture-Western
UFD1LHMOX110940518544348 Affinity Capture-Western
NPLOC4UFD1L11320011574150 16322459 18586029 Affinity Capture-Western; Two-hybrid
NPLOC4UFD1L12079811574150 16322459 18586029 Affinity Capture-Western; Two-hybrid
SELSUFD1L12093415215856 Affinity Capture-Western
SELSUFD1L11320015215856 Affinity Capture-Western
VCPUFD1L11320017872946 18199748 Affinity Capture-Western
VCPUFD1L11325817872946 18199748 Affinity Capture-Western
SVIPUFD1L11320017872946 Co-fractionation
SVIPUFD1L12922217872946 Co-fractionation
VCPIP1UFD1L11320019615732 Affinity Capture-MS
VCPIP1UFD1L12312519615732 Affinity Capture-MS
UBL4AUFD1L11320019615732 Affinity Capture-MS
UBL4AUFD1L11388519615732 Affinity Capture-MS
RAE1UFD1L11320019615732 Affinity Capture-MS
RAE1UFD1L11405419615732 Affinity Capture-MS
USP13UFD1L11446519615732 Affinity Capture-MS
USP13UFD1L11320019615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
UFD1LSC16395507, SC16407017, rs1057457, rs1547931, rs2073728, rs2238769, rs5746744, rs5992403, rs756658 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:109353
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040718-150'