AutismKB 2.0

Annotation Details for KDM6A


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Basic Information Top
Gene Symbol:KDM6A ( DKFZp686A03225,MGC141941,UTX,bA386N14.2 )
Gene Full Name: lysine (K)-specific demethylase 6A
Band: Xp11.3
Quick LinksEntrez ID:7403; OMIM: 300128; Uniprot ID:KDM6A_HUMAN; ENSEMBL ID: ENSG00000147050; HGNC ID: 12637
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus17500065
GO:0005654TAS-nucleoplasm-
GO:0035097IDA-histone methyltransferase complex17500065
GO:0044666IDA-MLL3/4 complex17500065
GO ID Evidence Qualifier GO_term References
GO:0000978IEA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0031490IEA-chromatin DNA binding-
GO:0032452TAS-histone demethylase activity-
GO:0042802IEA-identical protein binding-
GO:0046872IEA-metal ion binding-
GO:0051213IEA-dioxygenase activity-
GO:0071558IEA-histone demethylase activity (H3-K27 specific)-
GO ID Evidence Qualifier GO_term References
GO:0001701IEA-in utero embryonic development-
GO:0001843IEA-neural tube closure-
GO:0003007IEA-heart morphogenesis-
GO:0003016IEA-respiratory system process-
GO:0010628IEA-positive regulation of gene expression-
GO:0032525IEA-somite rostral/caudal axis specification-
GO:0035264IEA-multicellular organism growth-
GO:0048333IEA-mesodermal cell differentiation-
GO:0048570IEA-notochord morphogenesis-
GO:0051568ISS-histone H3-K4 methylation17178841
GO:0055114IEA-oxidation-reduction process-
GO:0060070IEA-canonical Wnt signaling pathway-
GO:0071557IEA-histone H3-K27 demethylation-
GO:0072358IEA-cardiovascular system development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
KDM6ARBBP511324617500065 17761849 Affinity Capture-MS; Affinity Capture-Western
KDM6ARBBP511186417500065 17761849 Affinity Capture-MS; Affinity Capture-Western
KDM6ATLE11129439854018 Two-hybrid
KDM6ATLE11132469854018 Two-hybrid
PAXIP1KDM6A11662517500065 17761849 17925232 Affinity Capture-MS; Affinity Capture-Western
PAXIP1KDM6A11324617500065 17761849 17925232 Affinity Capture-MS; Affinity Capture-Western
WDR5KDM6A11627217761849 Affinity Capture-MS
WDR5KDM6A11324617761849 Affinity Capture-MS
NCOA6KDM6A11324617761849 19047629 Affinity Capture-MS
NCOA6KDM6A11669117761849 19047629 Affinity Capture-MS
ZNF281KDM6A11707417761849 Affinity Capture-MS
ZNF281KDM6A11324617761849 Affinity Capture-MS
PPP6R3KDM6A12057917761849 Affinity Capture-MS
PPP6R3KDM6A11324617761849 Affinity Capture-MS
N4BP2KDM6A12084817761849 Affinity Capture-MS
N4BP2KDM6A11324617761849 Affinity Capture-MS
MLL3KDM6A12183517761849 Affinity Capture-MS
MLL3KDM6A11324617761849 Affinity Capture-MS
C13orf23KDM6A12317817761849 Affinity Capture-MS
C13orf23KDM6A11324617761849 Affinity Capture-MS
MLL2KDM6A11375817761849 Affinity Capture-MS
MLL2KDM6A11324617761849 Affinity Capture-MS
ASH2LKDM6A11452817761849 Affinity Capture-MS
ASH2LKDM6A11324617761849 Affinity Capture-MS
HIST3H3KDM6A11389517761849 Biochemical Activity
HIST3H3KDM6A11324617761849 Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1095419
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-081105-56'