Gene Symbol:	VAV2 ( - )
Gene Full Name:	vav 2 guanine nucleotide exchange factor
Band:	9q34.2
Quick Links	Entrez ID:7410; OMIM: 600428; Uniprot ID:VAV2_HUMAN; ENSEMBL ID: ENSG00000160293; HGNC ID: 12658
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0001784	IPI	-	phosphotyrosine residue binding	20624904
GO:0005085	EXP	-	guanyl-nucleotide exchange factor activity	8990121
GO:0005085	TAS	-	guanyl-nucleotide exchange factor activity	-
GO:0005089	TAS	-	Rho guanyl-nucleotide exchange factor activity	-
GO:0005154	IEA	-	epidermal growth factor receptor binding	-
GO:0005515	IPI	-	protein binding	11390470
GO:0046872	IEA	-	metal ion binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0001525	IEA	-	angiogenesis	-
GO:0007165	TAS	-	signal transduction	7762982
GO:0007264	IEA	-	small GTPase mediated signal transduction	-
GO:0008361	IGI	-	regulation of cell size	22467863
GO:0008361	IGI	NOT	regulation of cell size	22467863
GO:0010468	IMP	-	regulation of gene expression	21810271
GO:0016477	IEA	-	cell migration	-
GO:0030032	IEA	-	lamellipodium assembly	-
GO:0030168	TAS	-	platelet activation	-
GO:0030193	IMP	-	regulation of blood coagulation	21810271
GO:0035023	IEA	-	regulation of Rho protein signal transduction	-
GO:0038095	TAS	-	Fc-epsilon receptor signaling pathway	-
GO:0038096	TAS	-	Fc-gamma receptor signaling pathway involved in phagocytosis	-
GO:0043065	TAS	-	positive regulation of apoptotic process	-
GO:0043087	IGI	-	regulation of GTPase activity	22467863
GO:0043547	IEA	-	positive regulation of GTPase activity	-
GO:0043552	IEA	-	positive regulation of phosphatidylinositol 3-kinase activity	-
GO:0048010	TAS	-	vascular endothelial growth factor receptor signaling pathway	-
GO:0048013	TAS	-	ephrin receptor signaling pathway	-
GO:0051056	TAS	-	regulation of small GTPase mediated signal transduction	-

Gene Symbol	Interactant	Interaction ID	References	Description
VAV2	CD19	113253	11080163	Affinity Capture-Western; Reconstituted Complex
VAV2	CD19	107368	11080163	Affinity Capture-Western; Reconstituted Complex
VAV2	CD44	113253	11606575	Affinity Capture-Western
VAV2	CD44	107398	11606575	Affinity Capture-Western
VAV2	EGFR	108276	10938113	Affinity Capture-Western
VAV2	EGFR	113253	10938113	Affinity Capture-Western
VAV2	GRB2	109142	11606575 12577067	Affinity Capture-MS; Affinity Capture-Western
VAV2	GRB2	113253	11606575 12577067	Affinity Capture-MS; Affinity Capture-Western
VAV2	PDGFRB	111185	10938113	Affinity Capture-Western
VAV2	PDGFRB	113253	10938113	Affinity Capture-Western
SOCS1	VAV2	114203	10022833	Affinity Capture-Western
SOCS1	VAV2	113253	10022833	Affinity Capture-Western

AutismKB 2.0

Annotation Details for VAV2