AutismKB 2.0

Annotation Details for VEGFC


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Basic Information Top
Gene Symbol:VEGFC ( Flt4-L,VRP )
Gene Full Name: vascular endothelial growth factor C
Band: 4q34.3
Quick LinksEntrez ID:7424; OMIM: 601528; Uniprot ID:VEGFC_HUMAN; ENSEMBL ID: ENSG00000150630; HGNC ID: 12682
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IBA-extracellular space-
GO:0016020IEA-membrane-
GO:0031093TAS-platelet alpha granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding21130043
GO:0008083IBA-growth factor activity-
GO:0042056IDA-chemoattractant activity19275959
GO:0043185IBA-vascular endothelial growth factor receptor 3 binding-
GO ID Evidence Qualifier GO_term References
GO:0001525IBA-angiogenesis-
GO:0001666IBA-response to hypoxia-
GO:0001938IBA-positive regulation of endothelial cell proliferation-
GO:0001954IEA-positive regulation of cell-matrix adhesion-
GO:0002052IEA-positive regulation of neuroblast proliferation-
GO:0002576TAS-platelet degranulation-
GO:0006929TAS-substrate-dependent cell migration8617204
GO:0007165TAS-signal transduction8617204
GO:0008284TAS-positive regulation of cell proliferation8617204
GO:0008285IEA-negative regulation of cell proliferation-
GO:0009887IEA-animal organ morphogenesis-
GO:0016331IEA-morphogenesis of embryonic epithelium-
GO:0030947IEA-regulation of vascular endothelial growth factor receptor signaling pathway-
GO:0031954IEA-positive regulation of protein autophosphorylation-
GO:0042493IEA-response to drug-
GO:0043536IEA-positive regulation of blood vessel endothelial cell migration-
GO:0045766IBA-positive regulation of angiogenesis-
GO:0045776IEA-negative regulation of blood pressure-
GO:0048010IBA-vascular endothelial growth factor receptor signaling pathway-
GO:0048010TAS-vascular endothelial growth factor receptor signaling pathway-
GO:0050714IEA-positive regulation of protein secretion-
GO:0050731IEA-positive regulation of peptidyl-tyrosine phosphorylation-
GO:0050918IEA-positive chemotaxis-
GO:0050930IDA-induction of positive chemotaxis19275959
GO:0051781IEA-positive regulation of cell division-
GO:0060754IDA-positive regulation of mast cell chemotaxis19275959
GO:1901492IEA-positive regulation of lymphangiogenesis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
VEGFCFLT41132678700872 Affinity Capture-Western
VEGFCFLT41086128700872 Affinity Capture-Western
VEGFCVEGFC1132679233800 Reconstituted Complex
Gene Symbol Interactant Interaction ID References Description
VEGFCFLT419475512810700 VEGF-C interacts with VEGFR-3. This interaction was modeled on a demonstrated interaction between human VEGF-C and VEGFR-3 from an unspecified species.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:109124
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040303-4'