AutismKB 2.0

Annotation Details for VIL1


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Basic Information Top
Gene Symbol:VIL1 ( D2S1471,VIL )
Gene Full Name: villin 1
Band: 2q35
Quick LinksEntrez ID:7429; OMIM: 193040; Uniprot ID:VILI_HUMAN; ENSEMBL ID: ENSG00000127831; HGNC ID: 12690
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001726IDA-ruffle15342783
GO:0005654IDA-nucleoplasm-
GO:0005737IEA-cytoplasm-
GO:0005886IDA-plasma membrane-
GO:0005902IDA-microvillus17182858
GO:0005903ISS-brush border-
GO:0030027IDA-lamellipodium16921170
GO:0030175IDA-filopodium15342783
GO:0032432IDA-actin filament bundle17182858
GO:0032433ISS-filopodium tip-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005509IDA-calcium ion binding11500485
GO:0005509IMP-calcium ion binding15272027
GO:0005515IPI-protein binding16921170
GO:0005546IDA-phosphatidylinositol-4,5-bisphosphate binding14594952
GO:0035727IDA-lysophosphatidic acid binding19808673
GO:0042802IPI-identical protein binding17606613
GO:0042803IDA-protein homodimerization activity17606613
GO:0043027ISS-cysteine-type endopeptidase inhibitor activity involved in apoptotic process-
GO:0051015IDA-actin filament binding11500485
GO ID Evidence Qualifier GO_term References
GO:0001951IEA-intestinal D-glucose absorption-
GO:0006461TAS-protein complex assembly2846586
GO:0006915IEA-apoptotic process-
GO:0007173IDA-epidermal growth factor receptor signaling pathway17229814
GO:0008360IDA-regulation of cell shape16921170
GO:0009617IDA-response to bacterium17182858
GO:0010634IDA-positive regulation of epithelial cell migration17229814
GO:0010634IGI-positive regulation of epithelial cell migration18054784
GO:0010634IMP-positive regulation of epithelial cell migration18054784
GO:0030041IDA-actin filament polymerization11500485
GO:0030042IDA-actin filament depolymerization11500485
GO:0030335IDA-positive regulation of cell migration16921170
GO:0030836IMP-positive regulation of actin filament depolymerization15272027
GO:0030855IEP-epithelial cell differentiation21492153
GO:0032233IDA-positive regulation of actin filament bundle assembly19808673
GO:0032532IEA-regulation of microvillus length-
GO:0035729IEA-cellular response to hepatocyte growth factor stimulus-
GO:0040018IEA-positive regulation of multicellular organism growth-
GO:0043154IEA-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-
GO:0045010IEA-actin nucleation-
GO:0051014IDA-actin filament severing16921170
GO:0051016IMP-barbed-end actin filament capping15272027
GO:0051125IDA-regulation of actin nucleation16921170
GO:0051693IDA-actin filament capping16921170
GO:0060327IDA-cytoplasmic actin-based contraction involved in cell motility15342783
GO:0061041ISS-regulation of wound healing-
GO:0071364IDA-cellular response to epidermal growth factor stimulus17229814
GO:0090004IEA-positive regulation of establishment of protein localization to plasma membrane-
GO:1902896IEA-terminal web assembly-
GO:2000392ISS-regulation of lamellipodium morphogenesis-
GO:2000394IGI-positive regulation of lamellipodium morphogenesis18054784
GO:2000394IMP-positive regulation of lamellipodium morphogenesis18054784
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
VIL1PPM1B11149017353931 Affinity Capture-MS
VIL1PPM1B11327017353931 Affinity Capture-MS
TEX11VIL111327016189514 Two-hybrid
TEX11VIL112109316189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98930
  • Data Attributes: MGI curated and HomoloGene calculated
No data