AutismKB 2.0

Annotation Details for VRK1


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Basic Information Top
Gene Symbol:VRK1 ( MGC117401,MGC138280,MGC142070,PCH1 )
Gene Full Name: vaccinia related kinase 1
Band: 14q32.2
Quick LinksEntrez ID:7443; OMIM: 602168; Uniprot ID:VRK1_HUMAN; ENSEMBL ID: ENSG00000100749; HGNC ID: 12718
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus22194607
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005730IDA-nucleolus-
GO:0005795IDA-Golgi stack19103756
GO:0005819IEA-spindle-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004672IDA-protein kinase activity22194607
GO:0004674IDA-protein serine/threonine kinase activity21543316
GO:0004674TAS-protein serine/threonine kinase activity-
GO:0005515IPI-protein binding15105425
GO:0005524IEA-ATP binding-
GO:0019901IDA-protein kinase binding22572157
GO:0031493IPI-nucleosomal histone binding22194607
GO:0035175IDA-histone kinase activity (H3-S10 specific)22194607
GO:0072354IDA-histone kinase activity (H3-T3 specific)22194607
GO ID Evidence Qualifier GO_term References
GO:0006468IDA-protein phosphorylation22194607
GO:0007077TAS-mitotic nuclear envelope disassembly-
GO:0007084TAS-mitotic nuclear envelope reassembly-
GO:0008360IBA-regulation of cell shape-
GO:0043987IDA-histone H3-S10 phosphorylation22194607
GO:0046777IDA-protein autophosphorylation21543316
GO:0051301IEA-cell division-
GO:0072355IDA-histone H3-T3 phosphorylation22194607
GO:0090166IDA-Golgi disassembly19103756
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
VRK1RAN11328218617507 Affinity Capture-MS; Affinity Capture-Western
VRK1RAN11183718617507 Affinity Capture-MS; Affinity Capture-Western
VRK1TP5311328210951572 15542844 Affinity Capture-Western; Biochemical Activity
VRK1TP5311301010951572 15542844 Affinity Capture-Western; Biochemical Activity
VRK1VRK111328210951572 Biochemical Activity
HIST2H3CVRK111328217938195 Biochemical Activity; Reconstituted Complex
HIST2H3CVRK112602517938195 Biochemical Activity; Reconstituted Complex
HIST2H2BEVRK111328217938195 Reconstituted Complex
HIST2H2BEVRK111394517938195 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1261847
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2709'