AutismKB 2.0

Annotation Details for VRK2


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Basic Information Top
Gene Symbol:VRK2 ( - )
Gene Full Name: vaccinia related kinase 2
Band: 2p16.1
Quick LinksEntrez ID:7444; OMIM: 602169; Uniprot ID:VRK2_HUMAN; ENSEMBL ID: ENSG00000028116; HGNC ID: 12719
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus16704422
GO:0005737IDA-cytoplasm16704422
GO:0005783IDA-endoplasmic reticulum22572157
GO:0005789IDA-endoplasmic reticulum membrane18286207
GO:0016021IEA-integral component of membrane-
GO:0031966IDA-mitochondrial membrane18286207
GO:0043234IDA-protein complex22572157
GO ID Evidence Qualifier GO_term References
GO:0004674IDA-protein serine/threonine kinase activity14645249
GO:0005515IPI-protein binding16963744
GO:0005524IEA-ATP binding-
GO:0019901IDA-protein kinase binding22572157
GO:0019904IDA-protein domain specific binding22572157
GO ID Evidence Qualifier GO_term References
GO:0006468TAS-protein phosphorylation9344656
GO:0008360IBA-regulation of cell shape-
GO:0016032IEA-viral process-
GO:0018105IBA-peptidyl-serine phosphorylation-
GO:0034599IMP-cellular response to oxidative stress17709393
GO:0043408IMP-regulation of MAPK cascade20679487
GO:0046777IDA-protein autophosphorylation14645249
GO:2000659IMP-regulation of interleukin-1-mediated signaling pathway18286207
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
VRK2CDC4211328320936779 Two-hybrid
VRK2CDC4210743320936779 Two-hybrid
VRK2RAN11328318617507 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
VRK2RAN11183718617507 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
VRK2TP5311328316704422 Affinity Capture-Western; Biochemical Activity
VRK2TP5311301016704422 Affinity Capture-Western; Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1917172
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1046'