AutismKB 2.0

Annotation Details for VTN


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Basic Information Top
Gene Symbol:VTN ( V75,VN,VNT )
Gene Full Name: vitronectin
Band: 17q11.2
Quick LinksEntrez ID:7448; OMIM: 193190; Uniprot ID:VTNC_HUMAN; ENSEMBL ID: ENSG00000109072; HGNC ID: 12724
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576NAS-extracellular region14718574
GO:0005576TAS-extracellular region-
GO:0005604IEA-basement membrane-
GO:0005615IDA-extracellular space1695900
GO:0005783IDA-endoplasmic reticulum-
GO:0005796IEA-Golgi lumen-
GO:0031012IDA-extracellular matrix1632457
GO:0031012IDAcolocalizes_withextracellular matrix20551380
GO:0031012ISScolocalizes_withextracellular matrix22261194
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0048237IEA-rough endoplasmic reticulum lumen-
GO:0070062IDA-extracellular exosome19199708
GO:0071062TAS-alphav-beta3 integrin-vitronectin complex19267251
GO:0072562IDA-blood microparticle22516433
GO ID Evidence Qualifier GO_term References
GO:0005044IEA-scavenger receptor activity-
GO:0005178IDA-integrin binding22505472
GO:0005178IPI-integrin binding8837777
GO:0005515IPI-protein binding8900153
GO:0005518IEA-collagen binding-
GO:0008201IEA-heparin binding-
GO:0030247IEA-polysaccharide binding-
GO:0042802IEA-identical protein binding-
GO:0050840IEA-extracellular matrix binding-
GO ID Evidence Qualifier GO_term References
GO:0006898IEA-receptor-mediated endocytosis-
GO:0006955IEA-immune response-
GO:0007155TAS-cell adhesion2418831
GO:0007160IDA-cell-matrix adhesion10022831
GO:0010811IEA-positive regulation of cell-substrate adhesion-
GO:0010951IDA-negative regulation of endopeptidase activity1695900
GO:0014911IDA-positive regulation of smooth muscle cell migration8837777
GO:0030195IC-negative regulation of blood coagulation1695900
GO:0030198TAS-extracellular matrix organization-
GO:0030449TAS-regulation of complement activation-
GO:0030949TAS-positive regulation of vascular endothelial growth factor receptor signaling pathway19267251
GO:0032092IDA-positive regulation of protein binding1695900
GO:0033627IDA-cell adhesion mediated by integrin8837777
GO:0035987IDA-endodermal cell differentiation23154389
GO:0048260IDA-positive regulation of receptor-mediated endocytosis8626514
GO:0048709IEA-oligodendrocyte differentiation-
GO:0050731IDA-positive regulation of peptidyl-tyrosine phosphorylation10022831
GO:0051258IEA-protein polymerization-
GO:0061302IDA-smooth muscle cell-matrix adhesion8837777
GO:0090303IC-positive regulation of wound healing8837777
GO:0097421IEA-liver regeneration-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
VTNAMPH11328712565847 Reconstituted Complex
VTNAMPH10677012565847 Reconstituted Complex
VTNEGF11328711796824 Reconstituted Complex
VTNEGF10827011796824 Reconstituted Complex
VTNFGF211328711796824 Reconstituted Complex
VTNFGF210853811796824 Reconstituted Complex
VTNIGF211328710342887 Reconstituted Complex
VTNIGF210970210342887 Reconstituted Complex
VTNIGFBP511328711751588 Reconstituted Complex
VTNIGFBP510970911751588 Reconstituted Complex
VTNKNG111328710887113 Reconstituted Complex
VTNKNG111002610887113 Reconstituted Complex
VTNSERPINE111328711113116 Reconstituted Complex
VTNSERPINE111109111113116 Reconstituted Complex
VTNPOMC1132872475499 Reconstituted Complex
VTNPOMC1114392475499 Reconstituted Complex
VTNPVR11328711437656 Reconstituted Complex
VTNPVR11177511437656 Reconstituted Complex
VTNTGFB111328711796824 Reconstituted Complex
VTNTGFB111289811796824 Reconstituted Complex
VTNTGFB211328711796824 Reconstituted Complex
VTNTGFB211290011796824 Reconstituted Complex
VTNVEGFA11326511796824 Reconstituted Complex
VTNVEGFA11328711796824 Reconstituted Complex
LACRTVTN12465911419941 Reconstituted Complex
LACRTVTN11328711419941 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98940
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041116-1'