AutismKB 2.0

Annotation Details for WHSC1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:WHSC1 ( FLJ23286,KIAA1090,MGC176638,MMSET,NSD2,REIIBP,TRX5,WHS )
Gene Full Name: Wolf-Hirschhorn syndrome candidate 1
Band: 4p16.3
Quick LinksEntrez ID:7468; OMIM: 602952; Uniprot ID:NSD2_HUMAN; ENSEMBL ID: ENSG00000109685; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus-
GO:0005654TAS-nucleoplasm-
GO:0005694IEA-chromosome-
GO:0005737IEA-cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0003682IEA-chromatin binding-
GO:0005515IPI-protein binding19481544
GO:0018024TAS-histone-lysine N-methyltransferase activity-
GO:0042799TAS-histone methyltransferase activity (H4-K20 specific)-
GO:0043565IEA-sequence-specific DNA binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0003149IEA-membranous septum morphogenesis-
GO:0003289IEA-atrial septum primum morphogenesis-
GO:0003290IEA-atrial septum secundum morphogenesis-
GO:0006303TAS-double-strand break repair via nonhomologous end joining-
GO:0006351IEA-transcription, DNA-templated-
GO:0009653TAS-anatomical structure morphogenesis9618163
GO:0010452IEA-histone H3-K36 methylation-
GO:0034770IEA-histone H4-K20 methylation-
GO:0048298IEA-positive regulation of isotype switching to IgA isotypes-
GO:0060348IEA-bone development-
GO:0070201IEA-regulation of establishment of protein localization-
GO:2001032IEA-regulation of double-strand break repair via nonhomologous end joining-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
WHSC1AR11330619481544 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
WHSC1AR10686219481544 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
WHSC1HDAC111330616197452 18156491 18172012 Affinity Capture-Western; Reconstituted Complex
WHSC1HDAC110931516197452 18156491 18172012 Affinity Capture-Western; Reconstituted Complex
WHSC1HDAC211330618156491 18172012 Affinity Capture-Western; Reconstituted Complex
WHSC1HDAC210931618156491 18172012 Affinity Capture-Western; Reconstituted Complex
SIN3BWHSC111330616197452 Affinity Capture-Western
SIN3BWHSC111690116197452 Affinity Capture-Western
KDM1AWHSC111330618156491 Affinity Capture-Western
KDM1AWHSC111666718156491 Affinity Capture-Western
SIN3AWHSC111330618156491 Affinity Capture-Western
SIN3AWHSC111743918156491 Affinity Capture-Western
WHSC1WHSC111330618156491 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1276574
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-2581'