AutismKB 2.0

Annotation Details for XPO1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:XPO1 ( CRM1,DKFZp686B1823,emb )
Gene Full Name: exportin 1 (CRM1 homolog, yeast)
Band: 2p15
Quick LinksEntrez ID:7514; OMIM: 602559; Uniprot ID:XPO1_HUMAN; ENSEMBL ID: ENSG00000082898; HGNC ID: 12825
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000776IDA-kinetochore17363900
GO:0005634IDA-nucleus-
GO:0005635TAS-nuclear envelope9368044
GO:0005642IDA-annulate lamellae12210765
GO:0005654TAS-nucleoplasm-
GO:0005730IDA-nucleolus23782956
GO:0005737IDA-cytoplasm23782956
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0015030IEA-Cajal body-
GO:0016020IDA-membrane19946888
GO:0030529IDA-intracellular ribonucleoprotein complex18809582
GO:0031965IDA-nuclear membrane-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0003723IEA-RNA binding-
GO:0005049IMP-nuclear export signal receptor activity12724356
GO:0005215TAS-transporter activity-
GO:0005487IMP-nucleocytoplasmic transporter activity12773398
GO:0005515IPI-protein binding10358091
GO:0008536IEA-Ran GTPase binding-
GO:0019904IEA-protein domain specific binding-
GO ID Evidence Qualifier GO_term References
GO:0000054IMP-ribosomal subunit export from nucleus12724356
GO:0000055IMP-ribosomal large subunit export from nucleus12773398
GO:0000056IMP-ribosomal small subunit export from nucleus12773398
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0006611IDA-protein export from nucleus22250199
GO:0006611IMP-protein export from nucleus12773398
GO:0007062TAS-sister chromatid cohesion-
GO:0010824IEA-regulation of centrosome duplication-
GO:0016032TAS-viral process-
GO:0034504IEA-protein localization to nucleus-
GO:0042176IEA-regulation of protein catabolic process-
GO:0042493IEA-response to drug-
GO:0043488TAS-regulation of mRNA stability-
GO:0046825IEA-regulation of protein export from nucleus-
GO:0051028IEA-mRNA transport-
GO:0075733TAS-intracellular transport of virus-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
XPO1ADAR11334811604520 Reconstituted Complex
XPO1ADAR10661711604520 Reconstituted Complex
XPO1APC10682112070164 Affinity Capture-Western; Reconstituted Complex
XPO1APC11334812070164 Affinity Capture-Western; Reconstituted Complex
XPO1AIRE10682320085707 Affinity Capture-MS
XPO1AIRE11334820085707 Affinity Capture-MS
XPO1ARNT10689812065584 Affinity Capture-Western
XPO1ARNT11334812065584 Affinity Capture-Western
XPO1BACH110704715175654 Affinity Capture-Western
XPO1BACH111334815175654 Affinity Capture-Western
XPO1CCND110706712529437 Reconstituted Complex
XPO1CCND111334812529437 Reconstituted Complex
XPO1CDKN1B10746111889117 12529437 Affinity Capture-Western; Reconstituted Complex
XPO1CDKN1B11334811889117 12529437 Affinity Capture-Western; Reconstituted Complex
XPO1CEBPD10748120805509 Affinity Capture-MS
XPO1CEBPD11334820805509 Affinity Capture-MS
XPO1RCC110752911932251 Reconstituted Complex
XPO1RCC111334811932251 Reconstituted Complex
XPO1CHEK110753612676962 Reconstituted Complex
XPO1CHEK111334812676962 Reconstituted Complex
XPO1CLN310761220562859 Affinity Capture-MS
XPO1CLN311334820562859 Affinity Capture-MS
XPO1CRK10778811839808 Two-hybrid
XPO1CRK11334811839808 Two-hybrid
XPO1EIF5A11334810381392 Reconstituted Complex
XPO1EIF5A10829910381392 Reconstituted Complex
XPO1HNF4A10941410882110 Reconstituted Complex
XPO1HNF4A11334810882110 Reconstituted Complex
XPO1CIITA11041612517958 18245089 Affinity Capture-Western; Reconstituted Complex
XPO1CIITA11334812517958 18245089 Affinity Capture-Western; Reconstituted Complex
XPO1FOXO411044911313479 Reconstituted Complex
XPO1FOXO411334811313479 Reconstituted Complex
XPO1PMS211140417148452 Affinity Capture-MS
XPO1PMS211334817148452 Affinity Capture-MS
XPO1RAN1118379323133 10779340 12070164 Affinity Capture-Western; Reconstituted Complex
XPO1RAN1133489323133 10779340 12070164 Affinity Capture-Western; Reconstituted Complex
XPO1RANBP111183810601307 10779340 Reconstituted Complex
XPO1RANBP111334810601307 10779340 Reconstituted Complex
XPO1RPS6KB111211216895915 Affinity Capture-Western
XPO1RPS6KB111334816895915 Affinity Capture-Western
XPO1SET11334815239126 Affinity Capture-Western
XPO1SET11231615239126 Affinity Capture-Western
XPO1SMARCB111248211782423 Affinity Capture-Western; Reconstituted Complex
XPO1SMARCB111334811782423 Affinity Capture-Western; Reconstituted Complex
XPO1UBC11334816196087 Affinity Capture-Western
XPO1UBC11316416196087 Affinity Capture-Western
NUP153XPO111334810202161 Reconstituted Complex
NUP153XPO111529710202161 Reconstituted Complex
SNUPNXPO111334810209022 Reconstituted Complex
SNUPNXPO111538410209022 Reconstituted Complex
NUP62XPO111716510330396 11425870 Affinity Capture-Western; Reconstituted Complex
NUP62XPO111334810330396 11425870 Affinity Capture-Western; Reconstituted Complex
NXT1XPO111334811149927 Reconstituted Complex
NXT1XPO111887511149927 Reconstituted Complex
NUP214XPO111334811425870 15239126 Affinity Capture-Western
NUP214XPO111371711425870 15239126 Affinity Capture-Western
RANBP3XPO111334811425870 12176322 Reconstituted Complex; Two-hybrid
RANBP3XPO111407011425870 12176322 Reconstituted Complex; Two-hybrid
NXF3XPO111334811545741 Two-hybrid
NXF3XPO112102511545741 Two-hybrid
HDAC3XPO111436811779848 17141982 Affinity Capture-Western
HDAC3XPO111334811779848 17141982 Affinity Capture-Western
NMD3XPO111334812724356 Affinity Capture-Western; Reconstituted Complex
NMD3XPO111925912724356 Affinity Capture-Western; Reconstituted Complex
SAP25XPO111334816449650 Affinity Capture-MS
SAP25XPO194101816449650 Affinity Capture-MS
NRIP1XPO111334817053781 Affinity Capture-Western
NRIP1XPO111384317053781 Affinity Capture-Western
CDCA4XPO111334817141982 Affinity Capture-Western; Reconstituted Complex
CDCA4XPO112036717141982 Affinity Capture-Western; Reconstituted Complex
SERTAD2XPO111334817141982 Affinity Capture-Western; Reconstituted Complex
SERTAD2XPO111513617141982 Affinity Capture-Western; Reconstituted Complex
MEPCEXPO111334817643375 Affinity Capture-MS
MEPCEXPO112112217643375 Affinity Capture-MS
Gene Symbol Interactant Interaction ID References Description
XPO1NPM131246516041368 An unspecified isoform of NPM1 (NPM) interacts with XPO1 (CRM1).
SNORD3AXPO119479815574333 Crm1 interacts with U3 snoRNA
NUPL2XPO121458310358091 NUPL2 (NLP-1) interacts with XPO1 (CRM-1).
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2144013
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070530-6'