Gene Symbol:	XRCC1 ( RCC )
Gene Full Name:	X-ray repair complementing defective repair in Chinese hamster cells 1
Band:	19q13.2
Quick Links	Entrez ID:7515; OMIM: 194360; Uniprot ID:XRCC1_HUMAN; ENSEMBL ID: ENSG00000073050; HGNC ID: 12828
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0000784	IEA	-	nuclear chromosome, telomeric region	-
GO:0005634	IDA	-	nucleus	-
GO:0005654	TAS	-	nucleoplasm	-
GO:0070522	IEA	-	ERCC4-ERCC1 complex	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0003684	IEA	-	damaged DNA binding	-
GO:0003909	TAS	-	DNA ligase activity	-
GO:0005515	IPI	-	protein binding	14755728
GO:0019899	IPI	-	enzyme binding	8532526
GO:1990599	IEA	-	3' overhang single-stranded DNA endodeoxyribonuclease activity	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0000012	IEA	-	single strand break repair	-
GO:0000724	TAS	-	double-strand break repair via homologous recombination	-
GO:0001666	IEA	-	response to hypoxia	-
GO:0006283	TAS	-	transcription-coupled nucleotide-excision repair	-
GO:0006288	TAS	-	base-excision repair, DNA ligation	-
GO:0006297	TAS	-	nucleotide-excision repair, DNA gap filling	-
GO:0006303	IEA	-	double-strand break repair via nonhomologous end joining	-
GO:0010033	IEA	-	response to organic substance	-
GO:0021766	IEA	-	hippocampus development	-
GO:0042493	IEA	-	response to drug	-
GO:0061819	IEA	-	telomeric DNA-containing double minutes formation	-
GO:1905765	IEA	-	negative regulation of protection from non-homologous end joining at telomere	-

Gene Symbol	Interactant	Interaction ID	References	Description
XRCC1	PARP1	106652	9584196 15044383	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
XRCC1	PARP1	113349	9584196 15044383	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
XRCC1	APEX1	106825	11707423	Far Western; Two-hybrid
XRCC1	APEX1	113349	11707423	Far Western; Two-hybrid
XRCC1	LIG3	113349	8264637 9136882 9705932 11163244 11352725 17353931	Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
XRCC1	LIG3	110168	8264637 9136882 9705932 11163244 11352725 17353931	Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
XRCC1	OGG1	111018	12933815	Reconstituted Complex; Two-hybrid
XRCC1	OGG1	113349	12933815	Reconstituted Complex; Two-hybrid
XRCC1	PCNA	113349	15107487	Affinity Capture-Western; Co-localization; FRET; Reconstituted Complex
XRCC1	PCNA	111142	15107487	Affinity Capture-Western; Co-localization; FRET; Reconstituted Complex
XRCC1	POLB	113349	8978692 11467963 15107487 15520167	Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybrid
XRCC1	POLB	111419	8978692 11467963 15107487 15520167	Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybrid
XRCC1	TP53	113010	15044383	Affinity Capture-Western
XRCC1	TP53	113349	15044383	Affinity Capture-Western
PNKP	XRCC1	116440	11163244 17353931	Affinity Capture-MS; Affinity Capture-Western; Far Western; Two-hybrid
PNKP	XRCC1	113349	11163244 17353931	Affinity Capture-MS; Affinity Capture-Western; Far Western; Two-hybrid
PARP2	XRCC1	113349	11948190	Affinity Capture-Western
PARP2	XRCC1	115350	11948190	Affinity Capture-Western
APTX	XRCC1	120191	15044383 15555565	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
APTX	XRCC1	113349	15044383 15555565	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NEIL1	XRCC1	122787	15260972	Reconstituted Complex
NEIL1	XRCC1	113349	15260972	Reconstituted Complex
NCAPG	XRCC1	122089	16543152	Affinity Capture-Western
NCAPG	XRCC1	113349	16543152	Affinity Capture-Western
CHD1L	XRCC1	113349	19661379	Affinity Capture-Western
CHD1L	XRCC1	114929	19661379	Affinity Capture-Western

AutismKB 2.0

Annotation Details for XRCC1