AutismKB 2.0

Annotation Details for XRCC2


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Basic Information Top
Gene Symbol:XRCC2 ( DKFZp781P0919 )
Gene Full Name: X-ray repair complementing defective repair in Chinese hamster cells 2
Band: 7q36.1
Quick LinksEntrez ID:7516; OMIM: 600375; Uniprot ID:XRCC2_HUMAN; ENSEMBL ID: ENSG00000196584; HGNC ID: 12829
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005657IDA-replication fork20207730
GO:0005737IEA-cytoplasm-
GO:0005813IDA-centrosome21276791
GO:0033063IDA-Rad51B-Rad51C-Rad51D-XRCC2 complex11751635
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0000150IBA-recombinase activity-
GO:0000400IDAcontributes_tofour-way junction DNA binding20207730
GO:0003690IBA-double-stranded DNA binding-
GO:0003697IBA-single-stranded DNA binding-
GO:0004520IBAcontributes_toendodeoxyribonuclease activity-
GO:0005515IPI-protein binding10749867
GO:0005524IEA-ATP binding-
GO:0008094IBA-DNA-dependent ATPase activity-
GO ID Evidence Qualifier GO_term References
GO:0000278IMP-mitotic cell cycle21276791
GO:0000707IBA-meiotic DNA recombinase assembly-
GO:0000724IMP-double-strand break repair via homologous recombination23149936
GO:0000731TAS-DNA synthesis involved in DNA repair-
GO:0000732TAS-strand displacement-
GO:0001701IEA-in utero embryonic development-
GO:0001756IEA-somitogenesis-
GO:0006281IGI-DNA repair10422536
GO:0006312IBA-mitotic recombination-
GO:0007098IMP-centrosome cycle21276791
GO:0007131IBA-reciprocal meiotic recombination-
GO:0010165IEA-response to X-ray-
GO:0010212IBA-response to ionizing radiation-
GO:0010332IEA-response to gamma radiation-
GO:0035264IEA-multicellular organism growth-
GO:0042148IDA-strand invasion11834724
GO:0043524IEA-negative regulation of neuron apoptotic process-
GO:0050769IEA-positive regulation of neurogenesis-
GO:0051321TAS-meiotic cell cycle9628903
GO:2000269IEA-regulation of fibroblast apoptotic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
XRCC2BLM11335012975363 Affinity Capture-Western; Reconstituted Complex
XRCC2BLM10711012975363 Affinity Capture-Western; Reconstituted Complex
XRCC2RAD5111335015065660 Co-localization
XRCC2RAD5111182515065660 Co-localization
XRCC2RAD51C11335011744692 11842113 Affinity Capture-Western
XRCC2RAD51C11182611744692 11842113 Affinity Capture-Western
XRCC2RAD51L111335011744692 Affinity Capture-Western
XRCC2RAD51L111182711744692 Affinity Capture-Western
XRCC2RAD51L311182910749867 11842113 12975363 15115758 Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybrid
XRCC2RAD51L311335010749867 11842113 12975363 15115758 Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1927345
  • Data Attributes: MGI curated and HomoloGene calculated
No data