AutismKB 2.0

Annotation Details for XRCC4


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Basic Information Top
Gene Symbol:XRCC4 ( - )
Gene Full Name: X-ray repair complementing defective repair in Chinese hamster cells 4
Band: 5q14.2
Quick LinksEntrez ID:7518; OMIM: 194363; Uniprot ID:XRCC4_HUMAN; ENSEMBL ID: ENSG00000152422; HGNC ID: 12831
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000793IDANOTcondensed chromosome12589063
GO:0005634IDA-nucleus9259561
GO:0005634NAS-nucleus16439205
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005829IDA-cytosol9259561
GO:0005958IDA-DNA-dependent protein kinase-DNA ligase 4 complex15194694
GO:0032807IDA-DNA ligase IV complex9242410
GO:0070419IDA-nonhomologous end joining complex20383123
GO ID Evidence Qualifier GO_term References
GO:0003677IDANOTDNA binding9259561
GO:0005515IPI-protein binding9809069
GO:0008022IPI-protein C-terminus binding9259561
GO:0016874IDANOTligase activity9242410
GO:0042802IPI-identical protein binding16169070
GO ID Evidence Qualifier GO_term References
GO:0006302IDA-double-strand break repair9242410
GO:0006303IDA-double-strand break repair via nonhomologous end joining12517771
GO:0006303IMP-double-strand break repair via nonhomologous end joining9809069
GO:0006303NAS-double-strand break repair via nonhomologous end joining16439205
GO:0006303TAS-double-strand break repair via nonhomologous end joining-
GO:0006310IEA-DNA recombination-
GO:0010165IDA-response to X-ray9242410
GO:0051103IDA-DNA ligation involved in DNA repair12517771
GO:0051351IDA-positive regulation of ligase activity9242410
GO:0071285IEA-cellular response to lithium ion-
GO:0075713TAS-establishment of integrated proviral latency-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
XRCC4ACTN111335216189514 Two-hybrid
XRCC4ACTN110660216189514 Two-hybrid
XRCC4CHD310753216169070 Two-hybrid
XRCC4CHD311335216169070 Two-hybrid
XRCC4XRCC611335215520013 Affinity Capture-Western
XRCC4XRCC610882215520013 Affinity Capture-Western
XRCC4LIG411335211702069 15520013 17567543 Affinity Capture-Western; Co-crystal Structure; Two-hybrid
XRCC4LIG411016911702069 15520013 17567543 Affinity Capture-Western; Co-crystal Structure; Two-hybrid
XRCC4NBN11076318458108 Two-hybrid
XRCC4NBN11335218458108 Two-hybrid
XRCC4PRKDC11157715520013 Affinity Capture-Western
XRCC4PRKDC11335215520013 Affinity Capture-Western
XRCC4SETMAR11335218773976 Affinity Capture-Western
XRCC4SETMAR11231718773976 Affinity Capture-Western
XRCC4UBC11335216412978 Affinity Capture-Western
XRCC4UBC11316416412978 Affinity Capture-Western
XRCC4VIM11335216169070 Two-hybrid
XRCC4VIM11327216169070 Two-hybrid
XRCC5XRCC411335315520013 Affinity Capture-Western
XRCC5XRCC411335215520013 Affinity Capture-Western
XRCC4XRCC411335216169070 17567543 Two-hybrid
C9orf82XRCC411335216169070 Two-hybrid
C9orf82XRCC412297116169070 Two-hybrid
IFFO1XRCC411335216189514 Two-hybrid
IFFO1XRCC411740716189514 Two-hybrid
PNKPXRCC411644017353931 Affinity Capture-MS
PNKPXRCC411335217353931 Affinity Capture-MS
NHEJ1XRCC412293117567543 Affinity Capture-Western; Two-hybrid
NHEJ1XRCC411335217567543 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1333799
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1755'