AutismKB 2.0

Annotation Details for YES1


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Basic Information Top
Gene Symbol:YES1 ( HsT441,P61-YES,Yes,c-yes )
Gene Full Name: v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
Band: 18p11.32
Quick LinksEntrez ID:7525; OMIM: 164880; Uniprot ID:YES_HUMAN; ENSEMBL ID: ENSG00000176105; HGNC ID: 12841
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005794IDA-Golgi apparatus20605918
GO:0005815IEA-microtubule organizing center-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005884IEA-actin filament-
GO:0005886IDA-plasma membrane20605918
GO:0005925IDA-focal adhesion21423176
GO:0031234IBA-extrinsic component of cytoplasmic side of plasma membrane-
GO:0070062IDA-extracellular exosome19199708
GO ID Evidence Qualifier GO_term References
GO:0001784IPI-phosphotyrosine residue binding20624904
GO:0004713EXP-protein tyrosine kinase activity1381360
GO:0004713TAS-protein tyrosine kinase activity-
GO:0004715TAS-non-membrane spanning protein tyrosine kinase activity19267251
GO:0005102IBA-receptor binding-
GO:0005154IEA-epidermal growth factor receptor binding-
GO:0005515IPI-protein binding15657067
GO:0005524IEA-ATP binding-
GO:0019899IPI-enzyme binding20605918
GO:0044325IPI-ion channel binding12538589
GO ID Evidence Qualifier GO_term References
GO:0006464TAS-cellular protein modification process2436037
GO:0007169IBA-transmembrane receptor protein tyrosine kinase signaling pathway-
GO:0015758IEA-glucose transport-
GO:0016477IBA-cell migration-
GO:0030154IBA-cell differentiation-
GO:0031295TAS-T cell costimulation-
GO:0036120IEA-cellular response to platelet-derived growth factor stimulus-
GO:0038083IBA-peptidyl-tyrosine autophosphorylation-
GO:0038096TAS-Fc-gamma receptor signaling pathway involved in phagocytosis-
GO:0042127IBA-regulation of cell proliferation-
GO:0043114TAS-regulation of vascular permeability19267251
GO:0045087IBA-innate immune response-
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
GO:0048013TAS-ephrin receptor signaling pathway-
GO:0050731IEA-positive regulation of peptidyl-tyrosine phosphorylation-
GO:0050900TAS-leukocyte migration-
GO:0071300IEA-cellular response to retinoic acid-
GO:0071560IEA-cellular response to transforming growth factor beta stimulus-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
YES1CD361133571715582 Affinity Capture-Western
YES1CD361073861715582 Affinity Capture-Western
YES1CDH111335712640114 Reconstituted Complex
YES1CDH110743412640114 Reconstituted Complex
YES1CSF1R1078237681396 Affinity Capture-Western
YES1CSF1R1133577681396 Affinity Capture-Western
YES1CTNND111335712640114 Affinity Capture-Western
YES1CTNND110788112640114 Affinity Capture-Western
YES1DOK111335711071635 Reconstituted Complex
YES1DOK110813111071635 Reconstituted Complex
YES1EPHB21083629632142 Reconstituted Complex
YES1EPHB21133579632142 Reconstituted Complex
YES1FYN11335712640114 Affinity Capture-Western
YES1FYN10881012640114 Affinity Capture-Western
YES1JAK21099208702385 Affinity Capture-Western
YES1JAK21133578702385 Affinity Capture-Western
YES1KIT11001511071635 Reconstituted Complex
YES1KIT11335711071635 Reconstituted Complex
YES1CD4611034611901164 Affinity Capture-Western
YES1CD4611335711901164 Affinity Capture-Western
YES1NPHS111092812668668 Affinity Capture-Western
YES1NPHS111335712668668 Affinity Capture-Western
YES1PECAM111120110858437 Affinity Capture-Western
YES1PECAM111335710858437 Affinity Capture-Western
YES1PTK211171912558988 Affinity Capture-Western
YES1PTK211335712558988 Affinity Capture-Western
YES1RASA11118561544885 Affinity Capture-Western
YES1RASA11133571544885 Affinity Capture-Western
YES1RPL1011205412138090 Affinity Capture-Western; Two-hybrid
YES1RPL1011335712138090 Affinity Capture-Western; Two-hybrid
SLC9A3R1YES111476910562288 Reconstituted Complex
SLC9A3R1YES111335710562288 Reconstituted Complex
LOC100506658YES111100411950934 Affinity Capture-Western
LOC100506658YES111335711950934 Affinity Capture-Western
TRPV4YES112188312538589 Affinity Capture-Western
TRPV4YES111335712538589 Affinity Capture-Western
OGTYES111335716434389 Biochemical Activity
OGTYES111404916434389 Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99147
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050126-1'