AutismKB 2.0

Annotation Details for SF1


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Basic Information Top
Gene Symbol:SF1 ( BBP,D11S636,MBBP,ZFM1,ZNF162 )
Gene Full Name: splicing factor 1
Band: 11q13.1
Quick LinksEntrez ID:7536; OMIM: 601516; Uniprot ID:SF01_HUMAN; ENSEMBL ID: ENSG00000168066; HGNC ID: 12950
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634NAS-nucleus7912130
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005681IDA-spliceosomal complex9731529
GO:0005840NAS-ribosome8752089
GO:0016604IEA-nuclear body-
GO ID Evidence Qualifier GO_term References
GO:0003714TAS-transcription corepressor activity9660765
GO:0003723IDA-RNA binding22658674
GO:0003723TAS-RNA binding8752089
GO:0005515IPI-protein binding16189514
GO:0008270IEA-zinc ion binding-
GO:0042802IPI-identical protein binding22365833
GO:0045131IEA-pre-mRNA branch point binding-
GO ID Evidence Qualifier GO_term References
GO:0000245NAS-spliceosomal complex assembly8752089
GO:0000389TAS-mRNA 3'-splice site recognition15647371
GO:0000398IC-mRNA splicing, via spliceosome9731529
GO:0000398TAS-mRNA splicing, via spliceosome-
GO:0006351IEA-transcription, DNA-templated-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0030238IEA-male sex determination-
GO:0030575IEA-nuclear body organization-
GO:0033327IEA-Leydig cell differentiation-
GO:0048662IEA-negative regulation of smooth muscle cell proliferation-
GO:0050810IEA-regulation of steroid biosynthetic process-
GO:1903507IEA-negative regulation of nucleic acid-templated transcription-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SF1APBB111336816055720 Affinity Capture-MS
SF1APBB110681916055720 Affinity Capture-MS
SF1TRIM2311336816189514 Two-hybrid
SF1TRIM2310686816189514 Two-hybrid
SF1EWSR11133689660765 Reconstituted Complex; Two-hybrid
SF1EWSR11084319660765 Reconstituted Complex; Two-hybrid
SF1FUS1087979660765 Reconstituted Complex
SF1FUS1133689660765 Reconstituted Complex
SF1PLSCR111137316189514 Two-hybrid
SF1PLSCR111336816189514 Two-hybrid
SF1SRC11336816002533 Affinity Capture-Western
SF1SRC11259216002533 Affinity Capture-Western
U2AF2SF11133689150140 9512519 16189514 Reconstituted Complex; Two-hybrid
U2AF2SF11164669150140 9512519 16189514 Reconstituted Complex; Two-hybrid
TAF15SF11138079660765 Reconstituted Complex
TAF15SF11133689660765 Reconstituted Complex
TCERG1SF111612011604498 16055720 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
TCERG1SF111336811604498 16055720 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
NCOR2SF111336816002533 Affinity Capture-Western
NCOR2SF111497416002533 Affinity Capture-Western
WBP4SF111636316055720 Affinity Capture-MS
WBP4SF111336816055720 Affinity Capture-MS
PRPF40ASF111336816055720 Affinity Capture-MS
PRPF40ASF112079216055720 Affinity Capture-MS
ITCHSF111336816055720 Affinity Capture-MS
ITCHSF112374716055720 Affinity Capture-MS
GAS7SF111409416055720 Affinity Capture-MS
GAS7SF111336816055720 Affinity Capture-MS
DDX17SF111336816189514 Two-hybrid
DDX17SF111577616189514 Two-hybrid
RBPMSSF111622016189514 Two-hybrid
RBPMSSF111336816189514 Two-hybrid
WWP2SF111336816189514 Two-hybrid
WWP2SF111624416189514 Two-hybrid
ZNF461SF111336816595694 Reconstituted Complex
ZNF461SF112492616595694 Reconstituted Complex
Gene Symbol Interactant Interaction ID References Description
U2AF2SF11515909512519 U2AF65 interacts with an unspecified isoform of SF1 (mBBP).
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1095403
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-2492'