AutismKB 2.0

Annotation Details for ZBTB16


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Basic Information Top
Gene Symbol:ZBTB16 ( PLZF,ZNF145 )
Gene Full Name: zinc finger and BTB domain containing 16
Band: 11q23.2
Quick LinksEntrez ID:7704; OMIM: 176797; Uniprot ID:ZBT16_HUMAN; ENSEMBL ID: ENSG00000109906; HGNC ID: 12930
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus9294197
GO:0005829TAS-cytosol-
GO:0005886IEA-plasma membrane-
GO:0016604IDA-nuclear body19648967
GO:0016605IDA-PML body9294197
GO:0016607IDA-nuclear speck8541544
GO:0017053IDA-transcriptional repressor complex12802276
GO ID Evidence Qualifier GO_term References
GO:0000980IDA-RNA polymerase II distal enhancer sequence-specific DNA binding12802276
GO:0001206IDA-transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding12802276
GO:0003677IDA-DNA binding12802276
GO:0003677NAS-DNA binding9294197
GO:0005515IPI-protein binding9294197
GO:0008022IEA-protein C-terminus binding-
GO:0019904IEA-protein domain specific binding-
GO:0042802IPI-identical protein binding9294197
GO:0042803IDA-protein homodimerization activity8622986
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter12802276
GO:0001823ISS-mesonephros development8541544
GO:0006351IEA-transcription, DNA-templated-
GO:0006915NAS-apoptotic process9294197
GO:0007417ISS-central nervous system development8541544
GO:0008285IEA-negative regulation of cell proliferation-
GO:0009880IEA-embryonic pattern specification-
GO:0009952IEA-anterior/posterior pattern specification-
GO:0016567IEA-protein ubiquitination-
GO:0030097IDA-hemopoiesis8541544
GO:0030097TAS-hemopoiesis9294197
GO:0030099TAS-myeloid cell differentiation9294197
GO:0032332IMP-positive regulation of chondrocyte differentiation21547890
GO:0034504IEA-protein localization to nucleus-
GO:0035116IEA-embryonic hindlimb morphogenesis-
GO:0035136IEA-forelimb morphogenesis-
GO:0042733IEA-embryonic digit morphogenesis-
GO:0043065IEA-positive regulation of apoptotic process-
GO:0043687TAS-post-translational protein modification-
GO:0045600IMP-positive regulation of fat cell differentiation21547890
GO:0045638ISS-negative regulation of myeloid cell differentiation8541544
GO:0045778IDA-positive regulation of ossification21547890
GO:0045892IDA-negative regulation of transcription, DNA-templated12802276
GO:0045892NAS-negative regulation of transcription, DNA-templated9294197
GO:0045893IDA-positive regulation of transcription, DNA-templated21547890
GO:0048133IEA-male germ-line stem cell asymmetric division-
GO:0051138IEA-positive regulation of NK T cell differentiation-
GO:0051216IDA-cartilage development21547890
GO:0061036IDA-positive regulation of cartilage development21547890
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ZBTB16AGTR110669114657020 Reconstituted Complex; Two-hybrid
ZBTB16AGTR111349814657020 Reconstituted Complex; Two-hybrid
ZBTB16AR10686219762545 Two-hybrid
ZBTB16AR11349819762545 Two-hybrid
ZBTB16BCL610707611175338 Reconstituted Complex; Two-hybrid
ZBTB16BCL611349811175338 Reconstituted Complex; Two-hybrid
ZBTB16BMI111349812408802 Affinity Capture-Western; Reconstituted Complex
ZBTB16BMI110711612408802 Affinity Capture-Western; Reconstituted Complex
ZBTB16RUNX1T110731010688654 11090081 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ZBTB16RUNX1T111349810688654 11090081 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ZBTB16CD8111349816169070 Two-hybrid
ZBTB16CD8110741316169070 Two-hybrid
ZBTB16CDK111349810497277 Affinity Capture-Western
ZBTB16CDK110742010497277 Affinity Capture-Western
ZBTB16CIDEA11349816169070 Two-hybrid
ZBTB16CIDEA10757016169070 Two-hybrid
ZBTB16DLST10808716169070 Two-hybrid
ZBTB16DLST11349816169070 Two-hybrid
ZBTB16HBEGF11349814597771 15219838 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ZBTB16HBEGF10817214597771 15219838 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ZBTB16ESR111349814521715 Reconstituted Complex
ZBTB16ESR110840314521715 Reconstituted Complex
ZBTB16FHL210856512145280 Affinity Capture-Western; Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
ZBTB16FHL211349812145280 Affinity Capture-Western; Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
ZBTB16FHL310856612145280 Phenotypic Enhancement
ZBTB16FHL311349812145280 Phenotypic Enhancement
ZBTB16GATA111349812242665 Affinity Capture-Western
ZBTB16GATA110889312242665 Affinity Capture-Western
ZBTB16GATA211349811964310 Affinity Capture-Western; Reconstituted Complex
ZBTB16GATA210889411964310 Affinity Capture-Western; Reconstituted Complex
ZBTB16GCSH11349816169070 Two-hybrid
ZBTB16GCSH10892316169070 Two-hybrid
ZBTB16NR3C111349814521715 Reconstituted Complex
ZBTB16NR3C110916514521715 Reconstituted Complex
ZBTB16GSTM410920316169070 Two-hybrid
ZBTB16GSTM411349816169070 Two-hybrid
ZBTB16HDAC11134989627120 9765306 11865059 15467736 16024608 Affinity Capture-Western; Reconstituted Complex
ZBTB16HDAC11093159627120 9765306 11865059 15467736 16024608 Affinity Capture-Western; Reconstituted Complex
ZBTB16HDAC211349815467736 Reconstituted Complex
ZBTB16HDAC210931615467736 Reconstituted Complex
ZBTB16MAGEA1111349816189514 Two-hybrid
ZBTB16MAGEA1111028416189514 Two-hybrid
ZBTB16MAP3K311037916169070 Two-hybrid
ZBTB16MAP3K311349816169070 Two-hybrid
ZBTB16PAFAH1B311349816169070 Two-hybrid
ZBTB16PAFAH1B311108716169070 Two-hybrid
ZBTB16PLSCR111137316189514 Two-hybrid
ZBTB16PLSCR111349816189514 Two-hybrid
ZBTB16PMAIP111137916169070 Two-hybrid
ZBTB16PMAIP111349816169070 Two-hybrid
ZBTB16PML1113849294197 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ZBTB16PML1134989294197 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ZBTB16PSMD211349816169070 Two-hybrid
ZBTB16PSMD211168116169070 Two-hybrid
ZBTB16PSMD1111349816169070 Two-hybrid
ZBTB16PSMD1111168916169070 Two-hybrid
ZBTB16RAB27A11349816169070 Two-hybrid
ZBTB16RAB27A11181116169070 Two-hybrid
ZBTB16RARA11349814521715 Reconstituted Complex; Two-hybrid
ZBTB16RARA11184914521715 Reconstituted Complex; Two-hybrid
ZBTB16TRIM2711349816189514 Two-hybrid
ZBTB16TRIM2711191916189514 Two-hybrid
ZBTB16TERF111349816169070 Two-hybrid
ZBTB16TERF111287216169070 Two-hybrid
ZBTB16TRAF211349816189514 Two-hybrid
ZBTB16TRAF211303816189514 Two-hybrid
ZBTB16UBC11349818348865 Affinity Capture-Western
ZBTB16UBC11316418348865 Affinity Capture-Western
ZBTB16SUMO111318818348865 Affinity Capture-Western
ZBTB16SUMO111349818348865 Affinity Capture-Western
ZBTB16VDR11349811719366 12460926 Affinity Capture-Western; Reconstituted Complex
ZBTB16VDR11326411719366 12460926 Affinity Capture-Western; Reconstituted Complex
ZBTB16ZNF2411349816169070 Two-hybrid
ZBTB16ZNF2411340316169070 Two-hybrid
ZBTB16ZBTB161134988622986 11865059 16024608 Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex
NCOR2ZBTB161134989256429 9765306 11865059 14982881 16024608 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR2ZBTB161149749256429 9765306 11865059 14982881 16024608 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOR1ZBTB161134989531570 11865059 16024608 Affinity Capture-Western; Reconstituted Complex
NCOR1ZBTB161149739531570 11865059 16024608 Affinity Capture-Western; Reconstituted Complex
SIN3BZBTB161134989627120 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SIN3BZBTB161169019627120 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SIN3AZBTB161134989627120 9765306 11719366 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SIN3AZBTB161174399627120 9765306 11719366 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ZBTB32ZBTB1611349810572087 Affinity Capture-Western; Two-hybrid
ZBTB32ZBTB1611796410572087 Affinity Capture-Western; Two-hybrid
HDAC5ZBTB1611533111929873 15467736 Affinity Capture-Western; Reconstituted Complex
HDAC5ZBTB1611349811929873 15467736 Affinity Capture-Western; Reconstituted Complex
HDAC4ZBTB1611349811929873 15467736 Affinity Capture-Western; Reconstituted Complex
HDAC4ZBTB1611510611929873 15467736 Affinity Capture-Western; Reconstituted Complex
HDAC7ZBTB1611349811929873 Reconstituted Complex
HDAC7ZBTB1611961311929873 Reconstituted Complex
TXNIPZBTB1611587212821938 Affinity Capture-Western
TXNIPZBTB1611349812821938 Affinity Capture-Western
HDAC6ZBTB1611349815467736 Affinity Capture-Western; Reconstituted Complex
HDAC6ZBTB1611533015467736 Affinity Capture-Western; Reconstituted Complex
HDAC3ZBTB1611436815467736 Reconstituted Complex
HDAC3ZBTB1611349815467736 Reconstituted Complex
HBXIPZBTB1611349816169070 Two-hybrid
HBXIPZBTB1611579616169070 Two-hybrid
LMTK3ZBTB1612534516169070 Two-hybrid
LMTK3ZBTB1611349816169070 Two-hybrid
PGAM5ZBTB1611349816169070 Two-hybrid
PGAM5ZBTB1612815416169070 Two-hybrid
FCHO1ZBTB1611349816169070 Two-hybrid
FCHO1ZBTB1611676416169070 Two-hybrid
FAM101BZBTB1611349816169070 Two-hybrid
FAM101BZBTB1613178716169070 Two-hybrid
COQ6ZBTB1611349816169070 Two-hybrid
COQ6ZBTB1611921216169070 Two-hybrid
ANAPC5ZBTB1611953716169070 Two-hybrid
ANAPC5ZBTB1611349816169070 Two-hybrid
TOLLIPZBTB1611349816169070 Two-hybrid
TOLLIPZBTB1611997816169070 Two-hybrid
HEATR2ZBTB1611349816169070 Two-hybrid
HEATR2ZBTB1612026016169070 Two-hybrid
CCDC109BZBTB1611349816169070 Two-hybrid
CCDC109BZBTB1612034516169070 Two-hybrid
THNSL2ZBTB1611349816169070 Two-hybrid
THNSL2ZBTB1612054916169070 Two-hybrid
WDR33ZBTB1612062016169070 Two-hybrid
WDR33ZBTB1611349816169070 Two-hybrid
LYARZBTB1611349816169070 Two-hybrid
LYARZBTB1612078016169070 Two-hybrid
LSM2ZBTB1611349816169070 Two-hybrid
LSM2ZBTB1612177816169070 Two-hybrid
CCDC130ZBTB1611349816169070 Two-hybrid
CCDC130ZBTB1612353616169070 Two-hybrid
QTRT1ZBTB1611349816169070 Two-hybrid
QTRT1ZBTB1612362316169070 Two-hybrid
DPM1ZBTB1611434016169070 Two-hybrid
DPM1ZBTB1611349816169070 Two-hybrid
EIF2S2ZBTB1611441116169070 Two-hybrid
EIF2S2ZBTB1611349816169070 Two-hybrid
CCDC85BZBTB1611349816189514 Two-hybrid
CCDC85BZBTB1611619816189514 Two-hybrid
LDOC1ZBTB1611716916189514 Two-hybrid
LDOC1ZBTB1611349816189514 Two-hybrid
VTA1ZBTB1611349816189514 Two-hybrid
VTA1ZBTB1611959516189514 Two-hybrid
ENOX1ZBTB1611349816189514 Two-hybrid
ENOX1ZBTB1612038516189514 Two-hybrid
CEP72ZBTB1611349816189514 Two-hybrid
CEP72ZBTB1612084416189514 Two-hybrid
CEP70ZBTB1611349816189514 Two-hybrid
CEP70ZBTB1612323416189514 Two-hybrid
KRTAP4-12ZBTB1611349816189514 Two-hybrid
KRTAP4-12ZBTB1612375616189514 Two-hybrid
SPOPZBTB1611349816189514 Two-hybrid
SPOPZBTB1611399316189514 Two-hybrid
HDXZBTB1612655920211142 Two-hybrid
HDXZBTB1611349820211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:103222
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-1989'