AutismKB 2.0

Annotation Details for ZBTB17


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Basic Information Top
Gene Symbol:ZBTB17 ( MIZ-1,ZNF151,ZNF60,pHZ-67 )
Gene Full Name: zinc finger and BTB domain containing 17
Band: 1p36.13
Quick LinksEntrez ID:7709; OMIM: 604084; Uniprot ID:ZBT17_HUMAN; ENSEMBL ID: ENSG00000116809; HGNC ID: 12936
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654TAS-nucleoplasm-
GO:0032993IMP-protein-DNA complex19160485
GO:0043234IDA-protein complex19160485
GO ID Evidence Qualifier GO_term References
GO:0000978IMP-RNA polymerase II core promoter proximal region sequence-specific DNA binding9312026
GO:0001047IDA-core promoter binding19160485
GO:0001077IDA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding9312026
GO:0001077IMP-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding9312026
GO:0001223IPI-transcription coactivator binding19160485
GO:0001228IMP-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding19160485
GO:0003700IDA-transcription factor activity, sequence-specific DNA binding12244100
GO:0005515IPI-protein binding9308237
GO:0008134IPI-transcription factor binding19160485
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001702IEA-gastrulation with mouth forming second-
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0007398IEA-ectoderm development-
GO:0008285IDA-negative regulation of cell proliferation19160485
GO:0036498TAS-IRE1-mediated unfolded protein response-
GO:0045786TAS-negative regulation of cell cycle12244100
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter9312026
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter19160485
GO:0071158IDA-positive regulation of cell cycle arrest19160485
GO:1903146IMP-regulation of mitophagy24912190
GO:1903955IMP-positive regulation of protein targeting to mitochondrion24912190
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ZBTB17DNMT3A11350315616584 Affinity Capture-Western
ZBTB17DNMT3A10812515616584 Affinity Capture-Western
ZBTB17EP30011350311283613 Affinity Capture-Western
ZBTB17EP30010834711283613 Affinity Capture-Western
ZBTB17HCFC111350312244100 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ZBTB17HCFC110930412244100 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ZBTB17HK311350311068878 Reconstituted Complex; Two-hybrid
ZBTB17HK310934811068878 Reconstituted Complex; Two-hybrid
ZBTB17MAX11350311283613 Reconstituted Complex
ZBTB17MAX11031911283613 Reconstituted Complex
ZBTB17MYC1135039312026 11283613 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ZBTB17MYC1106949312026 11283613 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TOPBP1ZBTB1711625612408820 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TOPBP1ZBTB1711350312408820 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
DIS3ZBTB1711350315231747 Two-hybrid
DIS3ZBTB1711655915231747 Two-hybrid
Gene Symbol Interactant Interaction ID References Description
ZBTB17HK217177011068878 HKII interacts with Miz-1. This interaction was modeled on a demonstrated interaction between rat HKII and human Miz-1.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:107410
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-090313-240'