AutismKB 2.0

Annotation Details for ZNF174


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Basic Information Top
Gene Symbol:ZNF174 ( ZSCAN8 )
Gene Full Name: zinc finger protein 174
Band: 16p13.3
Quick LinksEntrez ID:7727; OMIM: 603900; Uniprot ID:ZN174_HUMAN; ENSEMBL ID: ENSG00000103343; HGNC ID: 12963
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005634NAS-nucleus7673192
GO:0005654IDA-nucleoplasm-
GO:0005829IDA-cytosol-
GO:0005886IDA-plasma membrane-
GO:0015629IDA-actin cytoskeleton-
GO ID Evidence Qualifier GO_term References
GO:0000981IBA-RNA polymerase II transcription factor activity, sequence-specific DNA binding-
GO:0003700IDA-transcription factor activity, sequence-specific DNA binding7673192
GO:0042803IPI-protein homodimerization activity15629724
GO:0044212IDA-transcription regulatory region DNA binding7673192
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter7673192
GO:0006351IEA-transcription, DNA-templated-
GO:0045892IDA-negative regulation of transcription, DNA-templated7673192
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ZNF174ZNF2411351610567577 Two-hybrid
ZNF174ZNF2411340310567577 Two-hybrid
ZNF174ZNF17411351610567577 11741982 Reconstituted Complex; Two-hybrid
ZNF192ZNF17411351610567577 Two-hybrid
ZNF192ZNF17411352910567577 Two-hybrid
ZNF434ZNF17412026520211142 Two-hybrid
ZNF434ZNF17411351620211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2686600
  • Data Attributes: HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018