AutismKB 2.0

Annotation Details for CACNA1B


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Basic Information Top
Gene Symbol:CACNA1B ( BIII,CACNL1A5,CACNN,Cav2.2 )
Gene Full Name: calcium channel, voltage-dependent, N type, alpha 1B subunit
Band: 9q34.3
Quick LinksEntrez ID:774; OMIM: 601012; Uniprot ID:CAC1B_HUMAN; ENSEMBL ID: ENSG00000148408; HGNC ID: 1389
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IBA-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0005891IEA-voltage-gated calcium channel complex-
GO:0030425IEA-dendrite-
GO:0043025IEA-neuronal cell body-
GO:0098793IEA-presynapse-
GO ID Evidence Qualifier GO_term References
GO:0005245TAS-voltage-gated calcium channel activity1321501
GO:0005262TAS-calcium channel activity-
GO:0005509IEA-calcium ion binding-
GO:0005515IPI-protein binding11438518
GO:0005524IEA-ATP binding-
GO:0008022IPI-protein C-terminus binding15728831
GO:0008331IBA-high voltage-gated calcium channel activity-
GO ID Evidence Qualifier GO_term References
GO:0006810TAS-transport1321501
GO:0007268TAS-chemical synaptic transmission9030575
GO:0007269IEA-neurotransmitter secretion-
GO:0007626IEA-locomotory behavior-
GO:0008016IEA-regulation of heart contraction-
GO:0008217IEA-regulation of blood pressure-
GO:0034765IEA-regulation of ion transmembrane transport-
GO:0048265IEA-response to pain-
GO:0051899TAS-membrane depolarization-
GO:0051924IEA-regulation of calcium ion transport-
GO:0070588IEA-calcium ion transmembrane transport-
GO:0086010IBA-membrane depolarization during action potential-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GNAO1CACNA1B10903711395521 Reconstituted Complex
GNAO1CACNA1B10722811395521 Reconstituted Complex
PDLIM5CACNA1B10722812665800 Affinity Capture-Western
PDLIM5CACNA1B11585712665800 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88296
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060531-44'