AutismKB 2.0

Annotation Details for ZP2


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Basic Information Top
Gene Symbol:ZP2 ( ZPA,Zp-2 )
Gene Full Name: zona pellucida glycoprotein 2 (sperm receptor)
Band: 16p12.3-p12.2
Quick LinksEntrez ID:7783; OMIM: 182888; Uniprot ID:ZP2_HUMAN; ENSEMBL ID: ENSG00000103310; HGNC ID: 13188
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005578IEA-proteinaceous extracellular matrix-
GO:0005771ISS-multivesicular body-
GO:0005783ISS-endoplasmic reticulum-
GO:0005794ISScolocalizes_withGolgi apparatus-
GO:0005886ISS-plasma membrane-
GO:0016021IEA-integral component of membrane-
GO:0030141ISScolocalizes_withsecretory granule-
GO:0031012ISS-extracellular matrix-
GO ID Evidence Qualifier GO_term References
GO:0015026TAS-coreceptor activity8385033
GO:0032190IPI-acrosin binding15950651
GO ID Evidence Qualifier GO_term References
GO:0006828ISSNOTmanganese ion transport-
GO:0007165IEA-signal transduction-
GO:0007339ISS-binding of sperm to zona pellucida22472438
GO:0007339TAS-binding of sperm to zona pellucida-
GO:0060046IDANOTregulation of acrosome reaction11751269
GO:0060468ISS-prevention of polyspermy22472438
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99214
  • Data Attributes: MGI curated and HomoloGene calculated
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018