AutismKB 2.0

Annotation Details for CACNA1S


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Basic Information Top
Gene Symbol:CACNA1S ( CACNL1A3,CCHL1A3,Cav1.1,HOKPP,HOKPP1,MHS5,TTPP1,hypoPP )
Gene Full Name: calcium channel, voltage-dependent, L type, alpha 1S subunit
Band: 1q32.1
Quick LinksEntrez ID:779; OMIM: 114208; Uniprot ID:CAC1S_HUMAN; ENSEMBL ID: ENSG00000081248; HGNC ID: 1397
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm11206130
GO:0005886IDA-plasma membrane11206130
GO:0005886TAS-plasma membrane-
GO:0005891IDA-voltage-gated calcium channel complex9852570
GO:0030315IDA-T-tubule17204937
GO:0031674IDA-I band11206130
GO:1990454ISS-L-type voltage-gated calcium channel complex-
GO ID Evidence Qualifier GO_term References
GO:0005245IDA-voltage-gated calcium channel activity9852570
GO:0005515IPI-protein binding25416956
GO:0008331IDA-high voltage-gated calcium channel activity9852570
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006816IDA-calcium ion transport9852570
GO:0006936IMP-muscle contraction17418573
GO:0034765IEA-regulation of ion transmembrane transport-
GO:0061337TAS-cardiac conduction-
GO:0070588IEA-calcium ion transmembrane transport-
GO:0071313ISS-cellular response to caffeine-
GO:0086010IBA-membrane depolarization during action potential-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SRICACNA1S1125959668070 Reconstituted Complex
SRICACNA1S1072339668070 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88294
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-051227-1'