AutismKB 2.0

Annotation Details for ZYX


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Basic Information Top
Gene Symbol:ZYX ( ESP-2,HED-2 )
Gene Full Name: zyxin
Band: 7q34
Quick LinksEntrez ID:7791; OMIM: 602002; Uniprot ID:ZYX_HUMAN; ENSEMBL ID: ENSG00000159840; HGNC ID: 13200
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001725IDA-stress fiber18297730
GO:0005634IDA-nucleus24036928
GO:0005829IDA-cytosol-
GO:0005886TAS-plasma membrane8940160
GO:0005887TAS-integral component of plasma membrane8940160
GO:0005913IDA-cell-cell adherens junction8940160
GO:0005925IDA-focal adhesion12417594
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0005515IPI-protein binding10831611
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0007155TAS-cell adhesion8940160
GO:0007160IC-cell-matrix adhesion24036928
GO:0007165TAS-signal transduction8940160
GO:0007179IMP-transforming growth factor beta receptor signaling pathway24036928
GO:0007229IMP-integrin-mediated signaling pathway24036928
GO:0007267TAS-cell-cell signaling8940160
GO:0016032IEA-viral process-
GO:0043149IMP-stress fiber assembly24036928
GO:0050727IEA-regulation of inflammatory response-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ZYXACTN111356910224105 11423549 Reconstituted Complex; Two-hybrid
ZYXACTN110660210224105 11423549 Reconstituted Complex; Two-hybrid
ZYXLASP111356915004028 Reconstituted Complex; Two-hybrid
ZYXLASP111012015004028 Reconstituted Complex; Two-hybrid
ZYXNEDD911081611782456 Two-hybrid
ZYXNEDD911356911782456 Two-hybrid
ZYXSREBF211259920936779 Two-hybrid
ZYXSREBF211356920936779 Two-hybrid
ZYXVASP11325110801818 10882740 Affinity Capture-Western; Two-hybrid
ZYXVASP11356910801818 10882740 Affinity Capture-Western; Two-hybrid
ENAHZYX12085810801818 12672821 Affinity Capture-Western; Protein-peptide; Two-hybrid
ENAHZYX11356910801818 12672821 Affinity Capture-Western; Protein-peptide; Two-hybrid
LATS1ZYX11456310831611 Affinity Capture-Western; Reconstituted Complex
LATS1ZYX11356910831611 Affinity Capture-Western; Reconstituted Complex
BCAR1ZYX11356911782456 Affinity Capture-Western
BCAR1ZYX11493411782456 Affinity Capture-Western
ZHX1ZYX11640612659632 Two-hybrid
ZHX1ZYX11356912659632 Two-hybrid
TESZYX11757212695497 Reconstituted Complex
TESZYX11356912695497 Reconstituted Complex
NEBLZYX11578415004028 Reconstituted Complex; Two-hybrid
NEBLZYX11356915004028 Reconstituted Complex; Two-hybrid
WNK1ZYX11356920936779 Two-hybrid
WNK1ZYX12240320936779 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:103072
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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