AutismKB 2.0

Annotation Details for DDR1


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Basic Information Top
Gene Symbol:DDR1 ( CAK,CD167,DDR,EDDR1,HGK2,MCK10,NEP,NTRK4,PTK3,PTK3A,RTK6,TRKE )
Gene Full Name: discoidin domain receptor tyrosine kinase 1
Band: 6p21.33
Quick LinksEntrez ID:780; OMIM: 600408; Uniprot ID:DDR1_HUMAN; ENSEMBL ID: ENSG00000204580; HGNC ID: 2730
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IDA-extracellular space16502470
GO:0005886TAS-plasma membrane-
GO:0005887IEA-integral component of plasma membrane-
GO:0043235IDA-receptor complex23382219
GO:0070062IDA-extracellular exosome19199708
GO ID Evidence Qualifier GO_term References
GO:0004714TAS-transmembrane receptor protein tyrosine kinase activity9659899
GO:0005515IPI-protein binding16337946
GO:0005518IDA-collagen binding9659899
GO:0005518IMP-collagen binding12065315
GO:0005524IEA-ATP binding-
GO:0038062IDA-protein tyrosine kinase collagen receptor activity9659899
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001558IEA-regulation of cell growth-
GO:0001952IEA-regulation of cell-matrix adhesion-
GO:0007155TAS-cell adhesion8302582
GO:0007566IEA-embryo implantation-
GO:0007595IEA-lactation-
GO:0008285IEA-negative regulation of cell proliferation-
GO:0010715IMP-regulation of extracellular matrix disassembly12065315
GO:0014909IMP-smooth muscle cell migration12065315
GO:0030198TAS-extracellular matrix organization-
GO:0038063IDA-collagen-activated tyrosine kinase receptor signaling pathway9659899
GO:0038063IMP-collagen-activated tyrosine kinase receptor signaling pathway12065315
GO:0038083IDA-peptidyl-tyrosine autophosphorylation21044884
GO:0043583IEA-ear development-
GO:0044319IMP-wound healing, spreading of cells12065315
GO:0046777IDA-protein autophosphorylation9659899
GO:0060444IEA-branching involved in mammary gland duct morphogenesis-
GO:0060749IEA-mammary gland alveolus development-
GO:0061302IMP-smooth muscle cell-matrix adhesion12065315
GO:0061564IEA-axon development-
GO:1990138IEA-neuron projection extension-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SHC1DDR11072349659899 Reconstituted Complex
SHC1DDR11123619659899 Reconstituted Complex
SNAPINDDR110723416169070 Two-hybrid
SNAPINDDR111710116169070 Two-hybrid
TM4SF1DDR110723416169070 Two-hybrid
TM4SF1DDR111024916169070 Two-hybrid
RGS2DDR110723416169070 Two-hybrid
RGS2DDR111192916169070 Two-hybrid
TTRDDR110723416169070 Two-hybrid
TTRDDR111312716169070 Two-hybrid
SNRNP40DDR110723416169070 Two-hybrid
SNRNP40DDR111480516169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
DDR1DDR1_novelSNP, rs1049622, rs1049623, rs1049628, rs1049633, rs1264319, rs1264320, rs1264326, rs2229933, rs2239518, rs2267641, rs8408, rs886422 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:99216
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060323-2'