AutismKB 2.0

Annotation Details for IL1R2


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Basic Information Top
Gene Symbol:IL1R2 ( CD121b,IL1RB,MGC47725 )
Gene Full Name: interleukin 1 receptor, type II
Band: 2q11.2
Quick LinksEntrez ID:7850; OMIM: 147811; Uniprot ID:IL1R2_HUMAN; ENSEMBL ID: ENSG00000115590; HGNC ID: 5994
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576IEA-extracellular region-
GO:0005737IEA-cytoplasm-
GO:0005886TAS-plasma membrane-
GO:0016021IEA-integral component of membrane-
GO ID Evidence Qualifier GO_term References
GO:0004908TAS-interleukin-1 receptor activity10191101
GO:0004910IEA-interleukin-1, Type II, blocking receptor activity-
GO:0005515IPI-protein binding1830582
GO:0019966IEA-interleukin-1 binding-
GO ID Evidence Qualifier GO_term References
GO:0006955TAS-immune response8898719
GO:0010955IEA-negative regulation of protein processing-
GO:0019221IEA-cytokine-mediated signaling pathway-
GO:0050712IEA-negative regulation of interleukin-1 alpha secretion-
GO:1900016IEA-negative regulation of cytokine production involved in inflammatory response-
GO:2000660IEA-negative regulation of interleukin-1-mediated signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
IL1R2IL1RN1136051834644 Affinity Capture-Western
IL1R2IL1RN1097721834644 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96546
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018