AutismKB 2.0

Annotation Details for USP7


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Basic Information Top
Gene Symbol:USP7 ( HAUSP,TEF1 )
Gene Full Name: ubiquitin specific peptidase 7 (herpes virus-associated)
Band: 16p13.2
Quick LinksEntrez ID:7874; OMIM: 602519; Uniprot ID:UBP7_HUMAN; ENSEMBL ID: ENSG00000187555; HGNC ID: 12630
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus11279055
GO:0005654TAS-nucleoplasm-
GO:0005694IEA-chromosome-
GO:0005829IDA-cytosol11279055
GO:0005829TAS-cytosol-
GO:0016604IDA-nuclear body16791210
GO:0016605IEA-PML body-
GO ID Evidence Qualifier GO_term References
GO:0002039IDA-p53 binding20096447
GO:0004197IMP-cysteine-type endopeptidase activity21745816
GO:0004843IDA-thiol-dependent ubiquitin-specific protease activity16964248
GO:0004843IMP-thiol-dependent ubiquitin-specific protease activity11923872
GO:0004843TAS-thiol-dependent ubiquitin-specific protease activity-
GO:0005515IPI-protein binding11279055
GO:0008022IPI-protein C-terminus binding12093161
GO:0008134IPI-transcription factor binding16964248
GO:0031625IPI-ubiquitin protein ligase binding11279055
GO:0036459TAS-thiol-dependent ubiquitinyl hydrolase activity-
GO ID Evidence Qualifier GO_term References
GO:0006283IMP-transcription-coupled nucleotide-excision repair22466612
GO:0006283TAS-transcription-coupled nucleotide-excision repair-
GO:0006511IEA-ubiquitin-dependent protein catabolic process-
GO:0007275IEA-multicellular organism development-
GO:0010216IMP-maintenance of DNA methylation21745816
GO:0016032IEA-viral process-
GO:0016567TAS-protein ubiquitination-
GO:0016579IDA-protein deubiquitination16964248
GO:0016579IMP-protein deubiquitination11923872
GO:0016579TAS-protein deubiquitination-
GO:0032088IDA-negative regulation of NF-kappaB transcription factor activity11279055
GO:0035520IDA-monoubiquitinated protein deubiquitination26280536
GO:0035616ISS-histone H2B conserved C-terminal lysine deubiquitination-
GO:0050821IDA-protein stabilization25172512
GO:0051090IDA-regulation of sequence-specific DNA binding transcription factor activity16964248
GO:1904353TAS-regulation of telomere capping25172512
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
USP7CRKL10778919615732 Affinity Capture-MS
USP7CRKL11362219615732 Affinity Capture-MS
USP7DNMT110812319615732 Affinity Capture-MS
USP7DNMT111362219615732 Affinity Capture-MS
USP7EIF4B11362219615732 Affinity Capture-MS
USP7EIF4B10829119615732 Affinity Capture-MS
USP7FOXO310859816964248 Affinity Capture-Western
USP7FOXO311362216964248 Affinity Capture-Western
USP7GTF2I11362219615732 Affinity Capture-MS
USP7GTF2I10922419615732 Affinity Capture-MS
USP7MAGEB211028717353931 Affinity Capture-MS
USP7MAGEB211362217353931 Affinity Capture-MS
USP7MCM411034119615732 Affinity Capture-MS
USP7MCM411362219615732 Affinity Capture-MS
USP7MCM511034219615732 Affinity Capture-MS
USP7MCM511362219615732 Affinity Capture-MS
USP7MCM611034319615732 Affinity Capture-MS
USP7MCM611362219615732 Affinity Capture-MS
USP7MDM211362216402859 16943424 17380154 17936559 Affinity Capture-Western; Co-crystal Structure; Co-fractionation; Protein-peptide
USP7MDM211035816402859 16943424 17380154 17936559 Affinity Capture-Western; Co-crystal Structure; Co-fractionation; Protein-peptide
USP7FOXO411044916964248 Affinity Capture-Western
USP7FOXO411362216964248 Affinity Capture-Western
USP7NUP9811098219615732 Affinity Capture-MS
USP7NUP9811362219615732 Affinity Capture-MS
USP7PPM1G11149119615732 Affinity Capture-MS
USP7PPM1G11362219615732 Affinity Capture-MS
USP7ATXN111221712093161 Affinity Capture-Western; Two-hybrid
USP7ATXN111362212093161 Affinity Capture-Western; Two-hybrid
USP7HLTF11248019615732 Affinity Capture-MS
USP7HLTF11362219615732 Affinity Capture-MS
USP7SRP6811260819615732 Affinity Capture-MS
USP7SRP6811362219615732 Affinity Capture-MS
USP7TP5311301011923872 16402859 17380154 17525743 Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-crystal Structure; Protein-peptide; Reconstituted Complex
USP7TP5311362211923872 16402859 17380154 17525743 Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-crystal Structure; Protein-peptide; Reconstituted Complex
USP7TRAF111362211279055 Reconstituted Complex
USP7TRAF111303711279055 Reconstituted Complex
USP7TRAF211303811279055 Reconstituted Complex
USP7TRAF211362211279055 Reconstituted Complex
USP7TRAF311362211279055 Reconstituted Complex
USP7TRAF311303911279055 Reconstituted Complex
USP7TRAF511304011279055 Reconstituted Complex
USP7TRAF511362211279055 Reconstituted Complex
USP7TRAF611304111279055 Reconstituted Complex
USP7TRAF611362211279055 Reconstituted Complex
USP7ZNF20711354019615732 Affinity Capture-MS
USP7ZNF20711362219615732 Affinity Capture-MS
TRAF4USP711497911279055 Reconstituted Complex
TRAF4USP711362211279055 Reconstituted Complex
GMPSUSP711436015749019 19615732 Affinity Capture-MS; Affinity Capture-Western; Co-purification
GMPSUSP711362215749019 19615732 Affinity Capture-MS; Affinity Capture-Western; Co-purification
HIST3H2BBUSP711362215749019 Biochemical Activity
HIST3H2BBUSP712610615749019 Biochemical Activity
RUVBL2USP711606717353931 Affinity Capture-MS
RUVBL2USP711362217353931 Affinity Capture-MS
RNPS1USP711612517353931 Affinity Capture-MS
RNPS1USP711362217353931 Affinity Capture-MS
CHFRUSP712086117442268 Affinity Capture-Western
CHFRUSP711362217442268 Affinity Capture-Western
PDCD6IPUSP711533217927229 Affinity Capture-Western
PDCD6IPUSP711362217927229 Affinity Capture-Western
CLSPNUSP712201519124652 Affinity Capture-Western; Biochemical Activity
CLSPNUSP711362219124652 Affinity Capture-Western; Biochemical Activity
HUWE1USP711538519615732 Affinity Capture-MS
HUWE1USP711362219615732 Affinity Capture-MS
SCML2USP711566119615732 Affinity Capture-MS
SCML2USP711362219615732 Affinity Capture-MS
USP19USP711607819615732 Affinity Capture-MS
USP19USP711362219615732 Affinity Capture-MS
KIF3AUSP711362219615732 Affinity Capture-MS
KIF3AUSP711630019615732 Affinity Capture-MS
FAM175BUSP711678419615732 Affinity Capture-MS
FAM175BUSP711362219615732 Affinity Capture-MS
DCAF4USP711754519615732 Affinity Capture-MS
DCAF4USP711362219615732 Affinity Capture-MS
C19orf62USP711885519615732 Affinity Capture-MS
C19orf62USP711362219615732 Affinity Capture-MS
RNF220USP711362219615732 Affinity Capture-MS
RNF220USP712048119615732 Affinity Capture-MS
YLPM1USP711362219615732 Affinity Capture-MS
YLPM1USP712111719615732 Affinity Capture-MS
BRCC3USP712259919615732 Affinity Capture-MS
BRCC3USP711362219615732 Affinity Capture-MS
C10orf119USP712297619615732 Affinity Capture-MS
C10orf119USP711362219615732 Affinity Capture-MS
TCEAL4USP712299819615732 Affinity Capture-MS
TCEAL4USP711362219615732 Affinity Capture-MS
CCDC6USP711372519615732 Affinity Capture-MS
CCDC6USP711362219615732 Affinity Capture-MS
FBXO38USP712351319615732 Affinity Capture-MS
FBXO38USP711362219615732 Affinity Capture-MS
AKAP1USP711381819615732 Affinity Capture-MS
AKAP1USP711362219615732 Affinity Capture-MS
RAE1USP711362219615732 Affinity Capture-MS
RAE1USP711405419615732 Affinity Capture-MS
PPIL4USP711362219615732 Affinity Capture-MS
PPIL4USP712446719615732 Affinity Capture-MS
DOCK7USP711362219615732 Affinity Capture-MS
DOCK7USP712452719615732 Affinity Capture-MS
USP14USP711455119615732 Affinity Capture-MS
USP14USP711362219615732 Affinity Capture-MS
BUB3USP711462119615732 Affinity Capture-MS
BUB3USP711362219615732 Affinity Capture-MS
TRIP12USP711473119615732 Affinity Capture-MS
TRIP12USP711362219615732 Affinity Capture-MS
TCEAL1USP711474519615732 Affinity Capture-MS
TCEAL1USP711362219615732 Affinity Capture-MS
BREUSP711494619615732 Affinity Capture-MS
BREUSP711362219615732 Affinity Capture-MS
USP11USP711386619615732 Affinity Capture-MS; Affinity Capture-Western
USP11USP711362219615732 Affinity Capture-MS; Affinity Capture-Western
KLHDC10USP711665220562859 Affinity Capture-MS
KLHDC10USP711362220562859 Affinity Capture-MS
SH3GLB1USP711928920562859 Affinity Capture-MS
SH3GLB1USP711362220562859 Affinity Capture-MS
ATG10USP711362220562859 Affinity Capture-MS
ATG10USP712374520562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2182061
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-3656'