AutismKB 2.0

Annotation Details for CAD


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Basic Information Top
Gene Symbol:CAD ( - )
Gene Full Name: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Band: 2p23.3
Quick LinksEntrez ID:790; OMIM: 114010; Uniprot ID:PYR1_HUMAN; ENSEMBL ID: ENSG00000084774; HGNC ID: 1424
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus15890648
GO:0005654IDA-nucleoplasm-
GO:0005829IDA-cytosol15890648
GO:0005829TAS-cytosol-
GO:0016020IDA-membrane19946888
GO:0016363IDA-nuclear matrix9525610
GO:0042995ISS-cell projection-
GO:0043025ISS-neuronal cell body-
GO:0043195ISS-terminal bouton-
GO:0043234IEA-protein complex-
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0004070ISS-aspartate carbamoyltransferase activity-
GO:0004070TAS-aspartate carbamoyltransferase activity-
GO:0004088ISS-carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity-
GO:0004088TAS-carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity-
GO:0004151IDA-dihydroorotase activity24332717
GO:0004151ISS-dihydroorotase activity-
GO:0004151TAS-dihydroorotase activity-
GO:0004672ISS-protein kinase activity-
GO:0005524ISS-ATP binding-
GO:0008270IDA-zinc ion binding24332717
GO:0019899IPI-enzyme binding15326225
GO:0042802ISS-identical protein binding-
GO:0070335ISS-aspartate binding-
GO ID Evidence Qualifier GO_term References
GO:0001889IEA-liver development-
GO:0006207IDA-'de novo' pyrimidine nucleobase biosynthetic process24332717
GO:0006207ISS-'de novo' pyrimidine nucleobase biosynthetic process-
GO:0006228IEA-UTP biosynthetic process-
GO:0006541ISS-glutamine metabolic process-
GO:0007507IEA-heart development-
GO:0007565IEA-female pregnancy-
GO:0007595IEA-lactation-
GO:0014075IEA-response to amine-
GO:0017144ISS-drug metabolic process-
GO:0018107ISS-peptidyl-threonine phosphorylation-
GO:0019240IEA-citrulline biosynthetic process-
GO:0031000IEA-response to caffeine-
GO:0031100IEA-animal organ regeneration-
GO:0032868IEA-response to insulin-
GO:0033574IEA-response to testosterone-
GO:0035690IEA-cellular response to drug-
GO:0042594IEA-response to starvation-
GO:0044205IEA-'de novo' UMP biosynthetic process-
GO:0046134TAS-pyrimidine nucleoside biosynthetic process-
GO:0046777ISS-protein autophosphorylation-
GO:0051414IEA-response to cortisol-
GO:0071364IEA-cellular response to epidermal growth factor stimulus-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NEDD4CAD10724316055720 Affinity Capture-MS
NEDD4CAD11081116055720 Affinity Capture-MS
SUMO2CAD10724319394292 Affinity Capture-MS
SUMO2CAD11249719394292 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1916969
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-021030-4'