Annotation Details for VKORC1

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Basic Information Top

Gene Symbol:	VKORC1 ( EDTP308,FLJ00289,IMAGE3455200,MGC2694,MST134,MST576,VKCFD2,VKOR )
Gene Full Name:	vitamin K epoxide reductase complex, subunit 1
Band:	16p11.2
Quick Links	Entrez ID:79001; OMIM: 608547; Uniprot ID:VKOR1_HUMAN; ENSEMBL ID: ENSG00000167397; HGNC ID: 23663
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:2 results
Molecular Function:3 results
Biological Process:7 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005789	TAS	-	endoplasmic reticulum membrane	-
GO:0016021	IEA	-	integral component of membrane	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0047057	EXP	-	vitamin-K-epoxide reductase (warfarin-sensitive) activity	23918929
GO:0047057	IDA	-	vitamin-K-epoxide reductase (warfarin-sensitive) activity	16270630
GO:0048038	IEA	-	quinone binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0007596	IMP	-	blood coagulation	16270630
GO:0017144	IMP	-	drug metabolic process	21127708
GO:0017187	IMP	-	peptidyl-glutamic acid carboxylation	20978134
GO:0042373	IDA	-	vitamin K metabolic process	16270630
GO:0042373	TAS	-	vitamin K metabolic process	-
GO:0055114	IEA	-	oxidation-reduction process	-
GO:0060348	ISS	-	bone development	-

Protein-Protein Interaction

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:106442
Data Attributes: MGI curated and HomoloGene calculated

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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