AutismKB 2.0

Annotation Details for DCTPP1


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Basic Information Top
Gene Symbol:DCTPP1 ( MGC5627,RS21C6,XTP3TPA )
Gene Full Name: dCTP pyrophosphatase 1
Band: 16p11.2
Quick LinksEntrez ID:79077; OMIM: NA; Uniprot ID:DCTP1_HUMAN; ENSEMBL ID: ENSG00000179958; HGNC ID: 28777
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus24467396
GO:0005739IDA-mitochondrion24467396
GO:0005829IDA-cytosol24467396
GO:0005829ISS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0000287ISS-magnesium ion binding-
GO:0005515IPI-protein binding16189514
GO:0032556IEA-pyrimidine deoxyribonucleotide binding-
GO:0042802IPI-identical protein binding16169070
GO:0047429IDA-nucleoside-triphosphate diphosphatase activity24467396
GO:0047429ISS-nucleoside-triphosphate diphosphatase activity-
GO:0047840IDA-dCTP diphosphatase activity24467396
GO ID Evidence Qualifier GO_term References
GO:0006253IMP-dCTP catabolic process24467396
GO:0009143IDA-nucleoside triphosphate catabolic process24467396
GO:0009143ISS-nucleoside triphosphate catabolic process-
GO:0042262IMP-DNA protection24467396
GO:0046076IMPNOTdTTP catabolic process24467396
GO:0051289IEA-protein homotetramerization-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DCTPP1PLK112252719596235 Affinity Capture-MS
DCTPP1PLK111136219596235 Affinity Capture-MS
DCTPP1WDYHV112040516189514 Two-hybrid
DCTPP1WDYHV112252716189514 Two-hybrid
DCTPP1NIF3L112192216189514 Two-hybrid
DCTPP1NIF3L112252716189514 Two-hybrid
DCTPP1DCTPP112252716169070 16189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1913672
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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