AutismKB 2.0

Annotation Details for PLEKHF1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PLEKHF1 ( APPD,MGC4090,PHAFIN1,ZFYVE15 )
Gene Full Name: pleckstrin homology domain containing, family F (with FYVE domain) member 1
Band: 19q12
Quick LinksEntrez ID:79156; OMIM: NA; Uniprot ID:PKHF1_HUMAN; ENSEMBL ID: ENSG00000166289; HGNC ID: 20764
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005764IDA-lysosome22115783
GO:0005765IC-lysosomal membrane22115783
GO:0005768IDAcolocalizes_withendosome22115783
GO:0010008IC-endosome membrane22115783
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding25416956
GO:0010314IDA-phosphatidylinositol-5-phosphate binding22115783
GO:0032266IDA-phosphatidylinositol-3-phosphate binding22115783
GO:0046872IEA-metal ion binding-
GO:0070273IDA-phosphatidylinositol-4-phosphate binding22115783
GO ID Evidence Qualifier GO_term References
GO:0006915IEA-apoptotic process-
GO:0007032IMP-endosome organization22115783
GO:0010508IDA-positive regulation of autophagy22115783
GO:0016050IMP-vesicle organization22115783
GO:0072659IMP-protein localization to plasma membrane22115783
GO:2001244IEA-positive regulation of intrinsic apoptotic signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PLEKHF1TNNT112257416189514 Two-hybrid
PLEKHF1TNNT111299216189514 Two-hybrid
PLEKHF1KIAA127912257416189514 Two-hybrid
PLEKHF1KIAA127911756716189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1919537
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1289'