AutismKB 2.0

Annotation Details for FAT4


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Basic Information Top
Gene Symbol:FAT4 ( CDHF14,CDHR11,FAT-J,FATJ,FLJ23056,FLJ77878,NBLA00548 )
Gene Full Name: FAT tumor suppressor homolog 4 (Drosophila)
Band: 4q28.1
Quick LinksEntrez ID:79633; OMIM: 612411; Uniprot ID:FAT4_HUMAN; ENSEMBL ID: ENSG00000196159; HGNC ID: 23109
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005886IEA-plasma membrane-
GO:0016021IEA-integral component of membrane-
GO:0045177IEA-apical part of cell-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0005509IEA-calcium ion binding-
GO:0005515IPI-protein binding22153077
GO ID Evidence Qualifier GO_term References
GO:0001658IEA-branching involved in ureteric bud morphogenesis-
GO:0003007IEA-heart morphogenesis-
GO:0007009IEA-plasma membrane organization-
GO:0007156IEA-homophilic cell adhesion via plasma membrane adhesion molecules-
GO:0007157ISS-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-
GO:0007219IEA-Notch signaling pathway-
GO:0008543IEA-fibroblast growth factor receptor signaling pathway-
GO:0021987ISS-cerebral cortex development-
GO:0022008ISS-neurogenesis-
GO:0035329ISS-hippo signaling-
GO:0043931IEA-ossification involved in bone maturation-
GO:0048565IEA-digestive tract development-
GO:0060122IEA-inner ear receptor stereocilium organization-
GO:0072137IEA-condensed mesenchymal cell proliferation-
GO:0072307IEA-regulation of metanephric nephron tubule epithelial cell differentiation-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:3045256
  • Data Attributes: HomoloGene calculated
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018