AutismKB 2.0

Annotation Details for DYNC2H1


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Basic Information Top
Gene Symbol:DYNC2H1 ( ATD3,DHC1b,DHC2,DNCH2,DYH1B,FLJ11756,hdhc11 )
Gene Full Name: dynein, cytoplasmic 2, heavy chain 1
Band: 11q22.3
Quick LinksEntrez ID:79659; OMIM: 603297; Uniprot ID:DYHC2_HUMAN; ENSEMBL ID: ENSG00000187240; HGNC ID: 2962
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005794IDA-Golgi apparatus8666668
GO:0005868IDA-cytoplasmic dynein complex21723285
GO:0005874IDA-microtubule21525035
GO:0005886IEA-plasma membrane-
GO:0005929TAS-cilium-
GO:0005930IEA-axoneme-
GO:0031514IEA-motile cilium-
GO:0045177IEA-apical part of cell-
GO:0070062IDA-extracellular exosome19056867
GO:0097542TAS-ciliary tip-
GO ID Evidence Qualifier GO_term References
GO:0003774NAS-motor activity8666668
GO:0005524IEA-ATP binding-
GO:0008569IDAcontributes_toATP-dependent microtubule motor activity, minus-end-directed21723285
GO ID Evidence Qualifier GO_term References
GO:0007030IDA-Golgi organization8666668
GO:0007368IEA-determination of left/right symmetry-
GO:0008105IEA-asymmetric protein localization-
GO:0009953IEA-dorsal/ventral pattern formation-
GO:0016485IEA-protein processing-
GO:0021522IEA-spinal cord motor neuron differentiation-
GO:0030326IEA-embryonic limb morphogenesis-
GO:0030900IEA-forebrain development-
GO:0035721IEA-intraciliary retrograde transport-
GO:0035735TAS-intraciliary transport involved in cilium assembly-
GO:0045880IEA-positive regulation of smoothened signaling pathway-
GO:0060976IEA-coronary vasculature development-
GO:1905515IEA-non-motile cilium assembly-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DYNC2H1DYNC2LI112278511907264 12432068 Affinity Capture-Western; Co-fractionation
DYNC2H1DYNC2LI111964411907264 12432068 Affinity Capture-Western; Co-fractionation
USP50DYNC2H112278519615732 Affinity Capture-MS
USP50DYNC2H113188419615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:107736
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-100217-1'