AutismKB 2.0

Annotation Details for SMC6


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Basic Information Top
Gene Symbol:SMC6 ( FLJ22116,FLJ35534,SMC-6,SMC6L1,hSMC6 )
Gene Full Name: structural maintenance of chromosomes 6
Band: 2p24.2
Quick LinksEntrez ID:79677; OMIM: 609387; Uniprot ID:SMC6_HUMAN; ENSEMBL ID: ENSG00000163029; HGNC ID: 20466
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000781IDA-chromosome, telomeric region17589526
GO:0000803ISS-sex chromosome-
GO:0005622IDA-intracellular-
GO:0005634IDA-nucleus11408570
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0016605IDA-PML body17589526
GO:0016607IEA-nuclear speck-
GO:0030915IDA-Smc5-Smc6 complex18086888
GO:0035061IDA-interchromatin granule11408570
GO:0035861IDA-site of double-strand break25931565
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding11408570
GO:0005524IEA-ATP binding-
GO:0031625IPI-ubiquitin protein ligase binding25931565
GO ID Evidence Qualifier GO_term References
GO:0000722IMP-telomere maintenance via recombination17589526
GO:0000724IEA-double-strand break repair via homologous recombination-
GO:0006974IDA-cellular response to DNA damage stimulus11408570
GO:0051984IMP-positive regulation of chromosome segregation25931565
GO:0090398IMP-cellular senescence17589526
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SMC6ALK12280214968112 Affinity Capture-MS
SMC6ALK10673914968112 Affinity Capture-MS
SMC6SMC512280211408570 Affinity Capture-Western
SMC6SMC511675411408570 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1914491
  • Data Attributes: MGI curated and HomoloGene calculated
No data