AutismKB 2.0

Annotation Details for TBL1XR1


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Basic Information Top
Gene Symbol:TBL1XR1 ( C21,DC42,FLJ12894,IRA1,TBLR1 )
Gene Full Name: transducin (beta)-like 1 X-linked receptor 1
Band: 3q26.32
Quick LinksEntrez ID:79718; OMIM: 608628; Uniprot ID:TBL1R_HUMAN; ENSEMBL ID: ENSG00000177565; HGNC ID: 29529
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000118IDAcolocalizes_withhistone deacetylase complex18326024
GO:0005634IDA-nucleus18193033
GO:0005654TAS-nucleoplasm-
GO:0005876IDA-spindle microtubule18326024
GO:0017053IDA-transcriptional repressor complex12628926
GO ID Evidence Qualifier GO_term References
GO:0003714IDA-transcription corepressor activity12628926
GO:0003714IGI-transcription corepressor activity15601853
GO:0005515IPI-protein binding12628926
GO:0008013IPI-beta-catenin binding18193033
GO:0042393IDA-histone binding15601853
GO:0044212IDA-transcription regulatory region DNA binding18193033
GO:0044212ISS-transcription regulatory region DNA binding-
GO:0047485IPI-protein N-terminus binding16893456
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter12628926
GO:0002021IEA-response to dietary excess-
GO:0006351IEA-transcription, DNA-templated-
GO:0016042IEA-lipid catabolic process-
GO:0016575IBA-histone deacetylation-
GO:0019216TAS-regulation of lipid metabolic process-
GO:0030814IEA-regulation of cAMP metabolic process-
GO:0035264IEA-multicellular organism growth-
GO:0043161ISS-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0045893IDA-positive regulation of transcription, DNA-templated18193033
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter18193033
GO:0050872IEA-white fat cell differentiation-
GO:0060070IMP-canonical Wnt signaling pathway18193033
GO:0060613IEA-fat pad development-
GO:0090207IEA-regulation of triglyceride metabolic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TBL1XR1EMD12283417620012 Affinity Capture-MS; Affinity Capture-Western
TBL1XR1EMD10832517620012 Affinity Capture-MS; Affinity Capture-Western
TBL1XR1SKI11238819032343 Affinity Capture-Western
TBL1XR1SKI12283419032343 Affinity Capture-Western
TBL1XR1TBL1X12283418202150 18374649 Affinity Capture-Western; Reconstituted Complex
TBL1XR1TBL1X11277018202150 18374649 Affinity Capture-Western; Reconstituted Complex
TBL1XR1HIST2H2BE11394512628926 Reconstituted Complex
TBL1XR1HIST2H2BE12283412628926 Reconstituted Complex
TBL1XR1HIST2H4A12283412628926 Reconstituted Complex
TBL1XR1HIST2H4A11396612628926 Reconstituted Complex
TBL1XR1HDAC311436811931768 18202150 Affinity Capture-MS; Affinity Capture-Western
TBL1XR1HDAC312283411931768 18202150 Affinity Capture-MS; Affinity Capture-Western
TBL1XR1NCOR111497311931768 12628926 14527417 18202150 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
TBL1XR1NCOR112283411931768 12628926 14527417 18202150 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
TBL1XR1UBE2E311574018202150 Affinity Capture-Western
TBL1XR1UBE2E312283418202150 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2441730
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1192'