AutismKB 2.0

Annotation Details for FZD3


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Basic Information Top
Gene Symbol:FZD3 ( Fz-3,hFz3 )
Gene Full Name: frizzled homolog 3 (Drosophila)
Band: 8p21.1
Quick LinksEntrez ID:7976; OMIM: 606143; Uniprot ID:FZD3_HUMAN; ENSEMBL ID: ENSG00000104290; HGNC ID: 4041
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm19038973
GO:0005886IDA-plasma membrane19038973
GO:0005886TAS-plasma membrane-
GO:0009986IEA-cell surface-
GO:0016021IEA-integral component of membrane-
GO:0016324IEA-apical plasma membrane-
GO:0016328IEA-lateral plasma membrane-
GO:0030424IEA-axon-
GO:0030425IEA-dendrite-
GO:0032433IEA-filopodium tip-
GO:0043025IEA-neuronal cell body-
GO:0048786IEA-presynaptic active zone-
GO ID Evidence Qualifier GO_term References
GO:0004930IEA-G-protein coupled receptor activity-
GO:0005515IPI-protein binding19277043
GO:0017147IPI-Wnt-protein binding19038973
GO:0017147NAS-Wnt-protein binding24431302
GO:0030165IPI-PDZ domain binding18256285
GO:0042813IC-Wnt-activated receptor activity19038973
GO:0042813NAS-Wnt-activated receptor activity24431302
GO ID Evidence Qualifier GO_term References
GO:0001736IEA-establishment of planar polarity-
GO:0001764IEA-neuron migration-
GO:0001843IEA-neural tube closure-
GO:0001942IEA-hair follicle development-
GO:0002052ISS-positive regulation of neuroblast proliferation-
GO:0007186IEA-G-protein coupled receptor signaling pathway-
GO:0007223TAS-Wnt signaling pathway, calcium modulating pathway-
GO:0030182ISS-neuron differentiation-
GO:0033278IEA-cell proliferation in midbrain-
GO:0036342IEA-post-anal tail morphogenesis-
GO:0036514IEA-dopaminergic neuron axon guidance-
GO:0036515IEA-serotonergic neuron axon guidance-
GO:0042472IEA-inner ear morphogenesis-
GO:0042493IEA-response to drug-
GO:0045976ISS-negative regulation of mitotic cell cycle, embryonic-
GO:0051602IEA-response to electrical stimulus-
GO:0060070IDA-canonical Wnt signaling pathway20802536
GO:0060071NAS-Wnt signaling pathway, planar cell polarity pathway24431302
GO:0061549ISS-sympathetic ganglion development-
GO:0071679IEA-commissural neuron axon guidance-
GO:1900118ISS-negative regulation of execution phase of apoptosis-
GO:1904693TAS-midbrain morphogenesis24431302
GO:1904938IEA-planar cell polarity pathway involved in axon guidance-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
WGFZD31387369147651 Co-localization
WGFZD31136899147651 Co-localization
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
FZD3rs2241802, rs2323019, rs352203, rs352210, rs352221, rs352226, rs3735725, rs3757999, rs880481, rs960914 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:108476
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070122-1'