AutismKB 2.0

Annotation Details for EHMT1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:EHMT1 ( DEL9q34,DKFZp667M072,EUHMTASE1,Eu-HMTase1,FLJ12879,FP13812,GLP,KIAA1876,KMT1D,bA188C12.1 )
Gene Full Name: euchromatic histone-lysine N-methyltransferase 1
Band: 9q34.3
Quick LinksEntrez ID:79813; OMIM: 607001; Uniprot ID:EHMT1_HUMAN; ENSEMBL ID: ENSG00000181090; HGNC ID: 24650
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IC-nucleus12004135
GO:0005634IDA-nucleus19144645
GO:0005634ISS-nucleus-
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005694IEA-chromosome-
GO:0016604IDA-nuclear body-
GO ID Evidence Qualifier GO_term References
GO:0002039IPI-p53 binding20118233
GO:0005515IPI-protein binding19061646
GO:0008168IDA-methyltransferase activity12004135
GO:0008270IEA-zinc ion binding-
GO:0016279IDA-protein-lysine N-methyltransferase activity20118233
GO:0018024IDA-histone-lysine N-methyltransferase activity12004135
GO:0046974ISS-histone methyltransferase activity (H3-K9 specific)-
GO:0046976ISS-histone methyltransferase activity (H3-K27 specific)-
GO:0070742IEA-C2H2 zinc finger domain binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0006306ISS-DNA methylation-
GO:0006325IDA-chromatin organization12004135
GO:0009790ISS-embryo development-
GO:0016571IDA-histone methylation12004135
GO:0018026ISS-peptidyl-lysine monomethylation-
GO:0018027IDA-peptidyl-lysine dimethylation20118233
GO:0045892ISS-negative regulation of transcription, DNA-templated-
GO:0051567IEA-histone H3-K9 methylation-
GO:0060992IEA-response to fungicide-
GO:0070734IEA-histone H3-K27 methylation-
GO:1901796TAS-regulation of signal transduction by p53 class mediator-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
EHMT1CTBP112290816702210 Affinity Capture-Western
EHMT1CTBP110786916702210 Affinity Capture-Western
EHMT1CTBP210787016702210 Affinity Capture-Western
EHMT1CTBP212290816702210 Affinity Capture-Western
EHMT1H3F3A10927217403666 Affinity Capture-MS
EHMT1H3F3A12290817403666 Affinity Capture-MS
EHMT1JARID210992319010785 Affinity Capture-Western
EHMT1JARID212290819010785 Affinity Capture-Western
EHMT1PCBD112290820211142 Two-hybrid
EHMT1PCBD111112520211142 Two-hybrid
EHMT1LZTR111385220211142 Two-hybrid
EHMT1LZTR112290820211142 Two-hybrid
EHMT1HIST1H3A12290820084102 Co-crystal Structure
EHMT1HIST1H3A11394620084102 Co-crystal Structure
TRIM15EHMT112290820211142 Two-hybrid
TRIM15EHMT112462620211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1924933
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040724-44'