AutismKB 2.0

Annotation Details for NANOG


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Basic Information Top
Gene Symbol:NANOG ( - )
Gene Full Name: Nanog homeobox
Band: 12p13.31
Quick LinksEntrez ID:79923; OMIM: 607937; Uniprot ID:NANOG_HUMAN; ENSEMBL ID: ENSG00000111704; HGNC ID: 20857
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IC-nucleus16153702
GO:0005634IDA-nucleus18932205
GO:0005654TAS-nucleoplasm-
GO:0005730IDA-nucleolus20458727
GO ID Evidence Qualifier GO_term References
GO:0003677IDA-DNA binding16153702
GO:0003700IDA-transcription factor activity, sequence-specific DNA binding16153702
GO:0003714ISS-transcription corepressor activity-
GO:0005515IPI-protein binding26687479
GO:0043565IEA-sequence-specific DNA binding-
GO ID Evidence Qualifier GO_term References
GO:0001714IDA-endodermal cell fate specification20713518
GO:0006351IEA-transcription, DNA-templated-
GO:0006355IDA-regulation of transcription, DNA-templated16153702
GO:0008283IMP-cell proliferation16501172
GO:0010468IMP-regulation of gene expression18388306
GO:0019827IEP-stem cell population maintenance15108323
GO:0030154IEP-cell differentiation16501172
GO:0035019IMP-somatic stem cell population maintenance18388306
GO:0035019TAS-somatic stem cell population maintenance-
GO:0045595IMP-regulation of cell differentiation16501172
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter20713518
GO:1903507IEA-negative regulation of nucleic acid-templated transcription-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NANOGMED1211529319036726 Affinity Capture-Western; Two-hybrid
NANOGMED1212300019036726 Affinity Capture-Western; Two-hybrid
NANOGSALL412300019060217 Affinity Capture-Western
NANOGSALL412142019060217 Affinity Capture-Western
RHOXF2NANOG12411920211142 Two-hybrid
RHOXF2NANOG12300020211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1919200
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018