AutismKB 2.0

Annotation Details for LHX3


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Basic Information Top
Gene Symbol:LHX3 ( CPHD3,DKFZp762A2013,LIM3,M2-LHX3 )
Gene Full Name: LIM homeobox 3
Band: 9q34.3
Quick LinksEntrez ID:8022; OMIM: 600577; Uniprot ID:LHX3_HUMAN; ENSEMBL ID: ENSG00000107187; HGNC ID: 6595
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005667IEA-transcription factor complex-
GO ID Evidence Qualifier GO_term References
GO:0000978IEA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0001076IEA-transcription factor activity, RNA polymerase II transcription factor binding-
GO:0001077IEA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0001085IPI-RNA polymerase II transcription factor binding26612202
GO:0001228IDA-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding15271874
GO:0043565IDA-sequence-specific DNA binding15271874
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001890IEA-placenta development-
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0008045IEA-motor neuron axon guidance-
GO:0009887TAS-animal organ morphogenesis10598593
GO:0021520IEA-spinal cord motor neuron cell fate specification-
GO:0021521IEA-ventral spinal cord interneuron specification-
GO:0021526IEA-medial motor column neuron differentiation-
GO:0021527IEA-spinal cord association neuron differentiation-
GO:0021983IEA-pituitary gland development-
GO:0030324IEA-lung development-
GO:0043066IEA-negative regulation of apoptotic process-
GO:0045893ISS-positive regulation of transcription, DNA-templated-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter15271874
GO:0048839IEP-inner ear development18407919
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
LHX3ISL11137189452425 Reconstituted Complex
LHX3ISL11098779452425 Reconstituted Complex
LHX3LHX11101639452425 Reconstituted Complex
LHX3LHX11137189452425 Reconstituted Complex
LHX3LMX1A1101949452425 Affinity Capture-Western; Reconstituted Complex
LHX3LMX1A1137189452425 Affinity Capture-Western; Reconstituted Complex
ISL2LHX31223189452425 Reconstituted Complex
ISL2LHX31137189452425 Reconstituted Complex
RLIMLHX311931910431247 Reconstituted Complex
RLIMLHX311371810431247 Reconstituted Complex
CITED2LHX311564910593900 Two-hybrid
CITED2LHX311371810593900 Two-hybrid
IFT172LHX311371810788441 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
IFT172LHX311758910788441 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:102673
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-980526-131'