Annotation Details for EDEM3

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Basic Information Top

Gene Symbol:	EDEM3 ( C1orf22 )
Gene Full Name:	ER degradation enhancer, mannosidase alpha-like 3
Band:	1q25.3
Quick Links	Entrez ID:80267; OMIM: 610214; Uniprot ID:EDEM3_HUMAN; ENSEMBL ID: ENSG00000116406; HGNC ID: 16787
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:4 results
Molecular Function:3 results
Biological Process:6 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005783	IBA	-	endoplasmic reticulum	-
GO:0005788	IEA	-	endoplasmic reticulum lumen	-
GO:0016020	IEA	-	membrane	-
GO:0044322	TAS	-	endoplasmic reticulum quality control compartment	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0004559	TAS	-	alpha-mannosidase activity	-
GO:0004571	IMP	-	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	25092655
GO:0005509	IEA	-	calcium ion binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0006486	IEA	-	protein glycosylation	-
GO:0006491	IBA	-	N-glycan processing	-
GO:0030433	IBA	-	ubiquitin-dependent ERAD pathway	-
GO:0030968	IBA	-	endoplasmic reticulum unfolded protein response	-
GO:1904382	IMP	-	mannose trimming involved in glycoprotein ERAD pathway	25092655
GO:1904382	TAS	-	mannose trimming involved in glycoprotein ERAD pathway	-

Protein-Protein Interaction

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:1 results

MGI ID: MGI:1914217
Data Attributes: MGI curated and HomoloGene calculated