AutismKB 2.0

Annotation Details for TET1


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Basic Information Top
Gene Symbol:TET1 ( CXXC6,FLJ10839,FLJ41442,KIAA1676,LCX,bA119F7.1 )
Gene Full Name: tet oncogene 1
Band: 10q21.3
Quick LinksEntrez ID:80312; OMIM: 607790; Uniprot ID:TET1_HUMAN; ENSEMBL ID: ENSG00000138336; HGNC ID: 29484
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IC-nucleus19372391
GO ID Evidence Qualifier GO_term References
GO:0003677IDA-DNA binding19372391
GO:0005506IDA-iron ion binding19372391
GO:0008270IEA-zinc ion binding-
GO:0070579IDA-methylcytosine dioxygenase activity19372391
GO:0070579IMP-methylcytosine dioxygenase activity21496894
GO ID Evidence Qualifier GO_term References
GO:0001826ISS-inner cell mass cell differentiation-
GO:0006351IEA-transcription, DNA-templated-
GO:0006493ISS-protein O-linked glycosylation-
GO:0008284IMP-positive regulation of cell proliferation25284789
GO:0016569IEA-covalent chromatin modification-
GO:0019827ISS-stem cell population maintenance-
GO:0031062IMP-positive regulation of histone methylation25284789
GO:0045944ISS-positive regulation of transcription from RNA polymerase II promoter-
GO:0055114IEA-oxidation-reduction process-
GO:0080111IMP-DNA demethylation21496894
GO:0090310IMP-negative regulation of methylation-dependent chromatin silencing21496894
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
TET1rs5030882 Gene overview in AlzGene
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Animal Model Top
  • MGI ID: MGI:1098693
  • Data Attributes: HomoloGene calculated
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018