AutismKB 2.0

Annotation Details for CUL5


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Basic Information Top
Gene Symbol:CUL5 ( VACM-1,VACM1 )
Gene Full Name: cullin 5
Band: 11q22.3
Quick LinksEntrez ID:8065; OMIM: 601741; Uniprot ID:CUL5_HUMAN; ENSEMBL ID: ENSG00000166266; HGNC ID: 2556
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0031466IDA-Cul5-RING ubiquitin ligase complex17636018
GO:0080008IBA-Cul4-RING E3 ubiquitin ligase complex-
GO ID Evidence Qualifier GO_term References
GO:0004842TAS-ubiquitin-protein transferase activity-
GO:0004872TAS-receptor activity9581826
GO:0005262TAS-calcium channel activity9581826
GO:0005515IPI-protein binding12504025
GO:0031625IDA-ubiquitin protein ligase binding17636018
GO:0061630IBAcontributes_toubiquitin protein ligase activity-
GO ID Evidence Qualifier GO_term References
GO:0000082TAS-G1/S transition of mitotic cell cycle8681378
GO:0006974IBA-cellular response to DNA damage stimulus-
GO:0007050TAS-cell cycle arrest8681378
GO:0008283TAS-cell proliferation9037604
GO:0008285TAS-negative regulation of cell proliferation8681378
GO:0016032IEA-viral process-
GO:0038128TAS-ERBB2 signaling pathway-
GO:0042787IBA-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-
GO:0043687TAS-post-translational protein modification-
GO:0070588IEA-calcium ion transmembrane transport-
GO:0097193TAS-intrinsic apoptotic signaling pathway9581826
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CUL5CISH11374316961462 Affinity Capture-MS
CUL5CISH10757416961462 Affinity Capture-MS
CUL5DIO211374315965468 Affinity Capture-Western
CUL5DIO210807815965468 Affinity Capture-Western
CUL5NEDD811374318805092 Co-crystal Structure
CUL5NEDD811081518805092 Co-crystal Structure
CUL5TCEB111278311384984 Reconstituted Complex
CUL5TCEB111374311384984 Reconstituted Complex
CUL5TCEB211374311384984 Reconstituted Complex
CUL5TCEB211278511384984 Reconstituted Complex
CUL5VHL11374311384984 Reconstituted Complex
CUL5VHL11326911384984 Reconstituted Complex
RBX1CUL511530110230407 11861641 18805092 Affinity Capture-Western; Co-crystal Structure; Two-hybrid
RBX1CUL511374310230407 11861641 18805092 Affinity Capture-Western; Co-crystal Structure; Two-hybrid
ANAPC11CUL511959110230407 Two-hybrid
ANAPC11CUL511374310230407 Two-hybrid
RNF7CUL511497710230407 Two-hybrid
RNF7CUL511374310230407 Two-hybrid
ASB6CUL512661216325183 Affinity Capture-Western
ASB6CUL511374316325183 Affinity Capture-Western
ASB7CUL512661316325183 Affinity Capture-Western
ASB7CUL511374316325183 Affinity Capture-Western
ASB12CUL512677616325183 Affinity Capture-Western
ASB12CUL511374316325183 Affinity Capture-Western
ASB1CUL511374316325183 Affinity Capture-Western
ASB1CUL511966816325183 Affinity Capture-Western
ASB2CUL511374316325183 Affinity Capture-Western
ASB2CUL511967416325183 Affinity Capture-Western
ASB3CUL511931717353931 Affinity Capture-MS
ASB3CUL511374317353931 Affinity Capture-MS
ASB4CUL511374317636018 Affinity Capture-Western
ASB4CUL511966917636018 Affinity Capture-Western
DCUN1D1CUL511374318826954 Reconstituted Complex
DCUN1D1CUL511992018826954 Reconstituted Complex
COPS6CUL511374319615732 Affinity Capture-MS
COPS6CUL511617619615732 Affinity Capture-MS
Gene Symbol Interactant Interaction ID References Description
RBX1CUL54996814564014 Rbx1 interacts with Cul5.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1922967
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-5426'