AutismKB 2.0

Annotation Details for NDFIP1


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Basic Information Top
Gene Symbol:NDFIP1 ( MGC10924,N4WBP5 )
Gene Full Name: Nedd4 family interacting protein 1
Band: 5q31.3
Quick LinksEntrez ID:80762; OMIM: 612050; Uniprot ID:NFIP1_HUMAN; ENSEMBL ID: ENSG00000131507; HGNC ID: 17592
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000139IEA-Golgi membrane-
GO:0005576IEA-extracellular region-
GO:0005938IEA-cell cortex-
GO:0010008IEA-endosome membrane-
GO:0016021IEA-integral component of membrane-
GO:0030054IEA-cell junction-
GO:0030425IEA-dendrite-
GO:0045202IEA-synapse-
GO:0048471IDA-perinuclear region of cytoplasm18776082
GO ID Evidence Qualifier GO_term References
GO:0004871IMP-signal transducer activity12761501
GO:0005515IPI-protein binding18776082
GO ID Evidence Qualifier GO_term References
GO:0002761IEA-regulation of myeloid leukocyte differentiation-
GO:0002829IEA-negative regulation of type 2 immune response-
GO:0006879IMP-cellular iron ion homeostasis18776082
GO:0007034IEA-vacuolar transport-
GO:0007165IEA-signal transduction-
GO:0010629IMP-negative regulation of gene expression18776082
GO:0030001IEA-metal ion transport-
GO:0031398IDA-positive regulation of protein ubiquitination25631046
GO:0031398IMP-positive regulation of protein ubiquitination18776082
GO:0032410IMP-negative regulation of transporter activity18776082
GO:0032713IEA-negative regulation of interleukin-4 production-
GO:0042130IEA-negative regulation of T cell proliferation-
GO:0043123IMP-positive regulation of I-kappaB kinase/NF-kappaB signaling12761501
GO:0045619IEA-regulation of lymphocyte differentiation-
GO:0045732IEA-positive regulation of protein catabolic process-
GO:0048294IEA-negative regulation of isotype switching to IgE isotypes-
GO:0048302IEA-regulation of isotype switching to IgG isotypes-
GO:0050728IEA-negative regulation of inflammatory response-
GO:0051224IMP-negative regulation of protein transport18776082
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NDFIP1SLC11A211095018776082 Affinity Capture-Western
NDFIP1SLC11A212329618776082 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1929601
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-2767'