AutismKB 2.0

Annotation Details for SETD7


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Basic Information Top
Gene Symbol:SETD7 ( FLJ21193,KIAA1717,KMT7,SET7,SET7/9,SET9 )
Gene Full Name: SET domain containing (lysine methyltransferase) 7
Band: 4q31.1
Quick LinksEntrez ID:80854; OMIM: 606594; Uniprot ID:SETD7_HUMAN; ENSEMBL ID: ENSG00000145391; HGNC ID: 30412
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654TAS-nucleoplasm-
GO:0005694IEA-chromosome-
GO:0005730IDA-nucleolus-
GO ID Evidence Qualifier GO_term References
GO:0002039IPI-p53 binding17108971
GO:0003682IEA-chromatin binding-
GO:0005515IPI-protein binding12540855
GO:0016279IDA-protein-lysine N-methyltransferase activity16415881
GO:0018024IDA-histone-lysine N-methyltransferase activity16415881
GO:0018024NAS-histone-lysine N-methyltransferase activity12514135
GO:0018024TAS-histone-lysine N-methyltransferase activity-
GO ID Evidence Qualifier GO_term References
GO:0006325NAS-chromatin organization12514135
GO:0006351IEA-transcription, DNA-templated-
GO:0006974IDA-cellular response to DNA damage stimulus23509280
GO:0018026IDA-peptidyl-lysine monomethylation17108971
GO:0018027IDA-peptidyl-lysine dimethylation17108971
GO:0034968IEA-histone lysine methylation-
GO:0045471IEA-response to ethanol-
GO:0045893IEA-positive regulation of transcription, DNA-templated-
GO:0051570IEA-regulation of histone H3-K9 methylation-
GO:0070828IDA-heterochromatin organization23509280
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SETD7DNMT112333219282482 Affinity Capture-Western; Biochemical Activity
SETD7DNMT110812319282482 Affinity Capture-Western; Biochemical Activity
SETD7ESR110840318471979 Biochemical Activity; Protein-peptide
SETD7ESR112333218471979 Biochemical Activity; Protein-peptide
SETD7RELA12333218650421 19262565 19864627 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SETD7RELA11190218650421 19262565 19864627 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SETD7TAF612333215099517 Affinity Capture-Western
SETD7TAF611274115099517 Affinity Capture-Western
SETD7TAF712333215099517 Affinity Capture-Western
SETD7TAF711274215099517 Affinity Capture-Western
SETD7TAF1012333215099517 16415881 Affinity Capture-Western; Biochemical Activity; Co-crystal Structure
SETD7TAF1011274415099517 16415881 Affinity Capture-Western; Biochemical Activity; Co-crystal Structure
SETD7TBP12333215099517 Affinity Capture-Western
SETD7TBP11277115099517 Affinity Capture-Western
SETD7TP5312333215525938 17108971 Biochemical Activity; Co-crystal Structure
SETD7TP5311301015525938 17108971 Biochemical Activity; Co-crystal Structure
SETD7HIST1H3A12333211779497 15525938 16415881 Biochemical Activity; Co-crystal Structure
SETD7HIST1H3A11394611779497 15525938 16415881 Biochemical Activity; Co-crystal Structure
SETD7HIST1H4A11395511779497 15525938 Biochemical Activity
SETD7HIST1H4A12333211779497 15525938 Biochemical Activity
SETD7L3MBTL112333218408754 Affinity Capture-Western; Reconstituted Complex
SETD7L3MBTL111748618408754 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1920501
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040718-156'