AutismKB 2.0

Annotation Details for FXR1


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Basic Information Top
Gene Symbol:FXR1 ( FXR1P )
Gene Full Name: fragile X mental retardation, autosomal homolog 1
Band: 3q26.33
Quick LinksEntrez ID:8087; OMIM: 600819; Uniprot ID:FXR1_HUMAN; ENSEMBL ID: ENSG00000114416; HGNC ID: 4023
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005730TAS-nucleolus10888599
GO:0005737IBA-cytoplasm-
GO:0005829IDA-cytosol-
GO:0005844IBA-polysome-
GO:0016020IDA-membrane19946888
GO:0030424IEA-axon-
GO:0035770IEA-ribonucleoprotein granule-
GO:0043034IEA-costamere-
GO:0043197IEA-dendritic spine-
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0002151IEA-G-quadruplex RNA binding-
GO:0003723IDA-RNA binding22658674
GO:0003729IBA-mRNA binding-
GO:0003730IEA-mRNA 3'-UTR binding-
GO:0005515IPI-protein binding7489725
GO:0033592IDA-RNA strand annealing activity17057366
GO:0042803IDA-protein homodimerization activity7489725
GO:0046982IDA-protein heterodimerization activity7489725
GO ID Evidence Qualifier GO_term References
GO:0006915TAS-apoptotic process9642279
GO:0007517IEA-muscle organ development-
GO:0017148IEA-negative regulation of translation-
GO:0030154IEA-cell differentiation-
GO:2000637IDA-positive regulation of gene silencing by miRNA17057366
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FXR1CRMP111376016169070 Two-hybrid
FXR1CRMP110779016169070 Two-hybrid
FXR1FMR11137607489725 8668200 Co-purification; Reconstituted Complex; Two-hybrid
FXR1FMR11086197489725 8668200 Co-purification; Reconstituted Complex; Two-hybrid
FXR1GBP211376016169070 Two-hybrid
FXR1GBP210890416169070 Two-hybrid
FXR2FXR11148907489725 8668200 Co-purification; Reconstituted Complex; Two-hybrid
FXR2FXR11137607489725 8668200 Co-purification; Reconstituted Complex; Two-hybrid
FXR1FXR11137607489725 Two-hybrid
CYFIP1FXR111376011438699 Affinity Capture-Western
CYFIP1FXR111680011438699 Affinity Capture-Western
CYFIP2FXR111376011438699 Two-hybrid
CYFIP2FXR111794511438699 Two-hybrid
PRSS23FXR111376016169070 Two-hybrid
PRSS23FXR111627916169070 Two-hybrid
C14orf1FXR111376016169070 Two-hybrid
C14orf1FXR111633216169070 Two-hybrid
LUC7L2FXR111376016169070 Two-hybrid
LUC7L2FXR111964616169070 Two-hybrid
C1orf103FXR111376016169070 Two-hybrid
C1orf103FXR112090516169070 Two-hybrid
KIAA1377FXR111376016169070 Two-hybrid
KIAA1377FXR112161716169070 Two-hybrid
GIGYF2FXR111376020696395 Affinity Capture-MS
GIGYF2FXR111752020696395 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104860
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-5431'