AutismKB 2.0

Annotation Details for CAMK2B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CAMK2B ( CAM2,CAMK2,CAMKB,MGC29528 )
Gene Full Name: calcium/calmodulin-dependent protein kinase II beta
Band: 7p13
Quick LinksEntrez ID:816; OMIM: 607707; Uniprot ID:KCC2B_HUMAN; ENSEMBL ID: ENSG00000058404; HGNC ID: 1461
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654TAS-nucleoplasm-
GO:0005737IBA-cytoplasm-
GO:0005815IEA-microtubule organizing center-
GO:0005829TAS-cytosol-
GO:0005886TAS-plasma membrane-
GO:0030666TAS-endocytic vesicle membrane-
GO:0033017IEA-sarcoplasmic reticulum membrane-
GO:0043005IBA-neuron projection-
GO ID Evidence Qualifier GO_term References
GO:0003779IEA-actin binding-
GO:0004674TAS-protein serine/threonine kinase activity-
GO:0004683IBA-calmodulin-dependent protein kinase activity-
GO:0005088TAS-Ras guanyl-nucleotide exchange factor activity-
GO:0005515IPI-protein binding25416956
GO:0005516IBA-calmodulin binding-
GO:0005524IEA-ATP binding-
GO:0042803IPI-protein homodimerization activity20668654
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0006468TAS-protein phosphorylation9060999
GO:0007165TAS-signal transduction9060999
GO:0010976ISS-positive regulation of neuron projection development-
GO:0014733TAS-regulation of skeletal muscle adaptation15294044
GO:0018105IBA-peptidyl-serine phosphorylation-
GO:0018107IBA-peptidyl-threonine phosphorylation-
GO:0035556IBA-intracellular signal transduction-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0046777IDA-protein autophosphorylation18817731
GO:0048169TAS-regulation of long-term neuronal synaptic plasticity18817731
GO:0051823TAS-regulation of synapse structural plasticity18817731
GO:0051924TAS-regulation of calcium ion transport15294044
GO:0060333TAS-interferon-gamma-mediated signaling pathway-
GO:0060998TAS-regulation of dendritic spine development18817731
GO:0061003ISS-positive regulation of dendritic spine morphogenesis-
GO:0090129ISS-positive regulation of synapse maturation-
GO:1900034TAS-regulation of cellular response to heat-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CAMK2BACTN410659611160423 Two-hybrid
CAMK2BACTN410726611160423 Two-hybrid
CAMK2BCAMK2A10726617353931 Affinity Capture-MS
CAMK2BCAMK2A10726517353931 Affinity Capture-MS
YWHABCAMK2B10726612619878 Biochemical Activity
YWHABCAMK2B11336112619878 Biochemical Activity
Gene Symbol Interactant Interaction ID References Description
CAMK2BACTN425890611160423 CAMK2B (CaMKII-beta) interacts with ACTN4 (alpha-Actinin 4).
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88257
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-9588'