AutismKB 2.0

Annotation Details for DOCK8


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Basic Information Top
Gene Symbol:DOCK8 ( FLJ00026,FLJ00152,FLJ00346,MRD2,ZIR8 )
Gene Full Name: dedicator of cytokinesis 8
Band: 9p24.3
Quick LinksEntrez ID:81704; OMIM: 611432; Uniprot ID:DOCK8_HUMAN; ENSEMBL ID: ENSG00000107099; HGNC ID: 19191
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0016020IDA-membrane19946888
GO:0031252IEA-cell leading edge-
GO ID Evidence Qualifier GO_term References
GO:0005085IEA-guanyl-nucleotide exchange factor activity-
GO:0005515IPI-protein binding22581261
GO ID Evidence Qualifier GO_term References
GO:0001771IEA-immunological synapse formation-
GO:0007264IEA-small GTPase mediated signal transduction-
GO:0007596TAS-blood coagulation-
GO:0036336IEA-dendritic cell migration-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0061485IMP-memory T cell proliferation22006977
GO:0070233IEA-negative regulation of T cell apoptotic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DOCK8CDC4212357715304341 Two-hybrid
DOCK8CDC4210743315304341 Two-hybrid
DOCK8RAC111181715304341 Two-hybrid
DOCK8RAC112357715304341 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1921396
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060503-743'