AutismKB 2.0

Annotation Details for NCOA3


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Basic Information Top
Gene Symbol:NCOA3 ( ACTR,AIB-1,AIB1,CAGH16,CTG26,KAT13B,MGC141848,RAC3,SRC-3,SRC3,TNRC14,TNRC16,TRAM-1,bHLHe42,pCIP )
Gene Full Name: nuclear receptor coactivator 3
Band: 20q13.12
Quick LinksEntrez ID:8202; OMIM: 601937; Uniprot ID:NCOA3_HUMAN; ENSEMBL ID: ENSG00000124151; HGNC ID: 7670
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin15831516
GO:0005634IDA-nucleus17223341
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005737IDA-cytoplasm17223341
GO:0005829IDA-cytosol-
GO:0043234IMP-protein complex11823864
GO:0070062IDA-extracellular exosome18570454
GO ID Evidence Qualifier GO_term References
GO:0003713IDA-transcription coactivator activity9238002
GO:0003713IMP-transcription coactivator activity17223341
GO:0003713NAS-transcription coactivator activity15572661
GO:0004402IDA-histone acetyltransferase activity9267036
GO:0005515IPI-protein binding10866661
GO:0016922IPI-ligand-dependent nuclear receptor binding18798693
GO:0030374IBA-ligand-dependent nuclear receptor transcription coactivator activity-
GO:0035257IDA-nuclear hormone receptor binding9267036
GO:0046966NAS-thyroid hormone receptor binding9346901
GO:0046982IMP-protein heterodimerization activity11823864
GO:0047485IPI-protein N-terminus binding12917342
GO:0050681NAS-androgen receptor binding15572661
GO:0097718IPI-disordered domain specific binding11823864
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0010628IMP-positive regulation of gene expression17223341
GO:0016573IEA-histone acetylation-
GO:0030521NAS-androgen receptor signaling pathway15572661
GO:0030522IBA-intracellular receptor signaling pathway-
GO:0032870IBA-cellular response to hormone stimulus-
GO:0035624TAS-receptor transactivation17223341
GO:0045618IMP-positive regulation of keratinocyte differentiation17082781
GO:0045893NAS-positive regulation of transcription, DNA-templated15572661
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter9267036
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter17082781
GO:0071392IDA-cellular response to estradiol stimulus15831516
GO:2001141IMP-regulation of RNA biosynthetic process17223341
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NCOA3ABL111384118765637 Affinity Capture-Western; Reconstituted Complex
NCOA3ABL110654318765637 Affinity Capture-Western; Reconstituted Complex
NCOA3AR11384110965917 11747336 14966121 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA3AR10686210965917 11747336 14966121 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
NCOA3CCND11138419832502 Affinity Capture-Western
NCOA3CCND11070679832502 Affinity Capture-Western
NCOA3BRCA111384114578343 16860316 Affinity Capture-Western; Protein-peptide; Reconstituted Complex
NCOA3BRCA110714014578343 16860316 Affinity Capture-Western; Protein-peptide; Reconstituted Complex
NCOA3CHUK11384111971985 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
NCOA3CHUK10756911971985 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
NCOA3CREBBP1138418616895 9192892 11076796 11971985 17043108 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-purification; Reconstituted Complex; Two-hybrid
NCOA3CREBBP1077778616895 9192892 11076796 11971985 17043108 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-purification; Reconstituted Complex; Two-hybrid
NCOA3DDX511384111250900 Phenotypic Enhancement; Reconstituted Complex
NCOA3DDX510802111250900 Phenotypic Enhancement; Reconstituted Complex
NCOA3EP30011384110655477 11823864 15145939 16923966 Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex
NCOA3EP30010834710655477 11823864 15145939 16923966 Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex
NCOA3ESR11138419192892 11050174 11250900 11389589 12714702 14766010 16923966 18645020 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex; Two-hybrid
NCOA3ESR11084039192892 11050174 11250900 11389589 12714702 14766010 16923966 18645020 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex; Two-hybrid
NCOA3ESR211384110681591 11389589 11500849 FRET; Reconstituted Complex
NCOA3ESR210840410681591 11389589 11500849 FRET; Reconstituted Complex
NCOA3ESRRA11384110598588 Reconstituted Complex
NCOA3ESRRA10840510598588 Reconstituted Complex
NCOA3ESRRB11384110598588 Reconstituted Complex
NCOA3ESRRB10840610598588 Reconstituted Complex
NCOA3ETS111384115788656 Affinity Capture-Western
NCOA3ETS110841415788656 Affinity Capture-Western
NCOA3ETS211384115788656 Affinity Capture-Western
NCOA3ETS210841515788656 Affinity Capture-Western
NCOA3FOS11384118511550 Affinity Capture-Western; Reconstituted Complex
NCOA3FOS10863618511550 Affinity Capture-Western; Reconstituted Complex
NCOA3NR5A210877211668176 Two-hybrid
NCOA3NR5A211384111668176 Two-hybrid
NCOA3NR3C111384111266503 12917342 Affinity Capture-Western; Reconstituted Complex
NCOA3NR3C110916511266503 12917342 Affinity Capture-Western; Reconstituted Complex
NCOA3NR4A111384112082103 Reconstituted Complex
NCOA3NR4A110940712082103 Reconstituted Complex
NCOA3PRMT111384111050077 Reconstituted Complex
NCOA3PRMT110951211050077 Reconstituted Complex
NCOA3IKBKB10976711971985 Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-fractionation; Reconstituted Complex
NCOA3IKBKB11384111971985 Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-fractionation; Reconstituted Complex
NCOA3SMAD211384118003620 Affinity Capture-MS
NCOA3SMAD211026218003620 Affinity Capture-MS
NCOA3SMAD311384118003620 Affinity Capture-MS
NCOA3SMAD311026318003620 Affinity Capture-MS
NCOA3NPAS211092314645221 Reconstituted Complex
NCOA3NPAS211384114645221 Reconstituted Complex
NCOA3PGR11384110757795 Reconstituted Complex
NCOA3PGR11126010757795 Reconstituted Complex
NCOA3PPARG11146410944516 11027271 11500849 FRET; Reconstituted Complex; Two-hybrid
NCOA3PPARG11384110944516 11027271 11500849 FRET; Reconstituted Complex; Two-hybrid
NCOA3RARA1138419192892 17475621 Reconstituted Complex; Two-hybrid
NCOA3RARA1118499192892 17475621 Reconstituted Complex; Two-hybrid
NCOA3RXRA1138419267036 11027271 11851396 15863722 Co-localization; Reconstituted Complex
NCOA3RXRA1121689267036 11027271 11851396 15863722 Co-localization; Reconstituted Complex
NCOA3TRIM2111261511971985 Affinity Capture-MS
NCOA3TRIM2111384111971985 Affinity Capture-MS
NCOA3STAT611265515145939 Affinity Capture-Western
NCOA3STAT611384115145939 Affinity Capture-Western
NCOA3NR2F111288310652338 Two-hybrid
NCOA3NR2F111384110652338 Two-hybrid
NCOA3THRA11384111117530 Affinity Capture-Western
NCOA3THRA11292311117530 Affinity Capture-Western
NCOA3NKX2-111293611076796 Two-hybrid
NCOA3NKX2-111384111076796 Two-hybrid
NCOA3UBC11316418593948 Affinity Capture-Western
NCOA3UBC11384118593948 Affinity Capture-Western
NCOA3VDR11326410224118 10681591 12893883 15919092 Co-localization; Reconstituted Complex; Two-hybrid
NCOA3VDR11384110224118 10681591 12893883 15919092 Co-localization; Reconstituted Complex; Two-hybrid
KAT2BNCOA31143759445475 Two-hybrid
KAT2BNCOA31138419445475 Two-hybrid
HIST4H4NCOA312573211163245 Biochemical Activity
HIST4H4NCOA311384111163245 Biochemical Activity
HIST3H3NCOA311389511163245 Biochemical Activity
HIST3H3NCOA311384111163245 Biochemical Activity
SRA1NCOA311532911250900 Phenotypic Enhancement
SRA1NCOA311384111250900 Phenotypic Enhancement
DDX17NCOA311577611250900 Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
DDX17NCOA311384111250900 Phenotypic Enhancement; Phenotypic Suppression; Reconstituted Complex; Two-hybrid
YWHAQNCOA311616811266503 Reconstituted Complex
YWHAQNCOA311384111266503 Reconstituted Complex
NR0B2NCOA311384111668176 Two-hybrid
NR0B2NCOA311401211668176 Two-hybrid
NCOA2NCOA311576111971985 18267973 Affinity Capture-MS; Affinity Capture-Western
NCOA2NCOA311384111971985 18267973 Affinity Capture-MS; Affinity Capture-Western
IKBKGNCOA311408911971985 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex
IKBKGNCOA311384111971985 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex
NCOR1NCOA311497312089344 Affinity Capture-Western; Reconstituted Complex
NCOR1NCOA311384112089344 Affinity Capture-Western; Reconstituted Complex
ANKRD11NCOA311888815184363 Reconstituted Complex; Two-hybrid
ANKRD11NCOA311384115184363 Reconstituted Complex; Two-hybrid
CARM1NCOA311576016923966 17043108 18511550 Affinity Capture-Western; Biochemical Activity; Co-fractionation; Co-purification; Reconstituted Complex
CARM1NCOA311384116923966 17043108 18511550 Affinity Capture-Western; Biochemical Activity; Co-fractionation; Co-purification; Reconstituted Complex
ATAD2NCOA311882717998543 Affinity Capture-Western
ATAD2NCOA311384117998543 Affinity Capture-Western
NCOA1NCOA311420018267973 Affinity Capture-Western
NCOA1NCOA311384118267973 Affinity Capture-Western
Gene Symbol Interactant Interaction ID References Description
ANKRD11NCOA318329715184363 ANCO-1 interacts with RAC3.
EBAG9NCOA325935915808510 AIB1 interacts with EBAG9 promoter.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1276535
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-051107-8'