AutismKB 2.0

Annotation Details for CAPN2


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Basic Information Top
Gene Symbol:CAPN2 ( CANP2,CANPL2,CANPml,FLJ39928,mCANP )
Gene Full Name: calpain 2, (m/II) large subunit
Band: 1q41
Quick LinksEntrez ID:824; OMIM: 114230; Uniprot ID:CAN2_HUMAN; ENSEMBL ID: ENSG00000162909; HGNC ID: 1479
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000785IEA-chromatin-
GO:0005634IEA-nucleus-
GO:0005737ISS-cytoplasm-
GO:0005764IEA-lysosome-
GO:0005783IDA-endoplasmic reticulum14559243
GO:0005794IDA-Golgi apparatus14559243
GO:0005829IDA-cytosol12150984
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane12150984
GO:0005886TAS-plasma membrane-
GO:0005925IDA-focal adhesion21423176
GO:0030425ISS-dendrite-
GO:0030864TAS-cortical actin cytoskeleton12150984
GO:0031143IDA-pseudopodium14559243
GO:0045121IDA-membrane raft14559243
GO:0045121IDAcolocalizes_withmembrane raft12150984
GO:0070062IDA-extracellular exosome19056867
GO:0097038IDA-perinuclear endoplasmic reticulum14559243
GO ID Evidence Qualifier GO_term References
GO:0004198IDA-calcium-dependent cysteine-type endopeptidase activity12150984
GO:0004198ISS-calcium-dependent cysteine-type endopeptidase activity-
GO:0005509IEA-calcium ion binding-
GO:0005515IPI-protein binding10639123
GO:0008092NAS-cytoskeletal protein binding12150984
GO:0008234TAS-cysteine-type peptidase activity2209092
GO:0046982IEA-protein heterodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0001666IEA-response to hypoxia-
GO:0001824IEA-blastocyst development-
GO:0006508ISS-proteolysis-
GO:0007520IEA-myoblast fusion-
GO:0016540IEA-protein autoprocessing-
GO:0022617TAS-extracellular matrix disassembly-
GO:0051493TAS-regulation of cytoskeleton organization12150984
GO:0051603IDA-proteolysis involved in cellular protein catabolic process12150984
GO:0071230ISS-cellular response to amino acid stimulus-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CAPN2BCL210706812000759 Biochemical Activity; Reconstituted Complex
CAPN2BCL210727412000759 Biochemical Activity; Reconstituted Complex
CAPN2BID10710612000759 Biochemical Activity
CAPN2BID10727412000759 Biochemical Activity
PTPRNCAPN210727411483505 Biochemical Activity
PTPRNCAPN211176211483505 Biochemical Activity
CAPNS1CAPN210727411517928 Co-crystal Structure
CAPNS1CAPN210727611517928 Co-crystal Structure
HNRNPA1CAPN210942017643375 Affinity Capture-MS
HNRNPA1CAPN210727417643375 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
CAPN2rs1153952, rs3738383, rs3767717 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:88264
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050320-69'