AutismKB 2.0

Annotation Details for FZD8


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Basic Information Top
Gene Symbol:FZD8 ( FZ-8,hFZ8 )
Gene Full Name: frizzled homolog 8 (Drosophila)
Band: 10p11.21
Quick LinksEntrez ID:8325; OMIM: 606146; Uniprot ID:FZD8_HUMAN; ENSEMBL ID: ENSG00000177283; HGNC ID: 4046
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005794IEA-Golgi apparatus-
GO:0016021TAS-integral component of membrane11295046
GO:1990851IEA-Wnt-Frizzled-LRP5/6 complex-
GO ID Evidence Qualifier GO_term References
GO:0004930IEA-G-protein coupled receptor activity-
GO:0005102IEA-receptor binding-
GO:0005515IPI-protein binding22682250
GO:0017147IEA-Wnt-protein binding-
GO:0030165IPI-PDZ domain binding18256285
GO:0031625IPI-ubiquitin protein ligase binding22575959
GO:0042813TAS-Wnt-activated receptor activity11295046
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0001525IEA-angiogenesis-
GO:0007186IEA-G-protein coupled receptor signaling pathway-
GO:0030182ISS-neuron differentiation-
GO:0033077IEA-T cell differentiation in thymus-
GO:0043507IEA-positive regulation of JUN kinase activity-
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
GO:0060070IMP-canonical Wnt signaling pathway22138402
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FZD8LRP611021911448771 Affinity Capture-Western
FZD8LRP611392111448771 Affinity Capture-Western
FZD8LRP511392111448771 Affinity Capture-Western
FZD8LRP511022011448771 Affinity Capture-Western
FZD8SUMO111318817549794 Affinity Capture-MS
FZD8SUMO111392117549794 Affinity Capture-MS
FZD8WNT111330811448771 Affinity Capture-Western
FZD8WNT111392111448771 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:108460
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-000328-3'