AutismKB 2.0

Annotation Details for HDAC10


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Basic Information Top
Gene Symbol:HDAC10 ( DKFZp761B039,HD10,MGC149722 )
Gene Full Name: histone deacetylase 10
Band: 22q13.33
Quick LinksEntrez ID:83933; OMIM: 608544; Uniprot ID:HDA10_HUMAN; ENSEMBL ID: ENSG00000100429; HGNC ID: 18128
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000118IDA-histone deacetylase complex11861901
GO:0005634IDA-nucleus11861901
GO:0005654IDA-nucleoplasm11726666
GO:0005654TAS-nucleoplasm-
GO:0005737IDA-cytoplasm11726666
GO ID Evidence Qualifier GO_term References
GO:0004407IDA-histone deacetylase activity11861901
GO:0004407TAS-histone deacetylase activity-
GO:0005515IPI-protein binding17172643
GO:0019899IPI-enzyme binding11861901
GO:0032041IEA-NAD-dependent histone deacetylase activity (H3-K14 specific)-
GO:0033558IDA-protein deacetylase activity17172643
GO:0042826IDA-histone deacetylase binding11861901
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter11726666
GO:0006325NAS-chromatin organization11861901
GO:0006351IEA-transcription, DNA-templated-
GO:0006355IDA-regulation of transcription, DNA-templated11861901
GO:0006476IDA-protein deacetylation17172643
GO:0014003IEA-oligodendrocyte development-
GO:0016575IDA-histone deacetylation11861901
GO:0045892IDA-negative regulation of transcription, DNA-templated11726666
GO:0070932IEA-histone H3 deacetylation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
HDAC10HDAC210931611739383 Affinity Capture-Western
HDAC10HDAC212381811739383 Affinity Capture-Western
HDAC10HSPA812381820032463 Affinity Capture-Western; Reconstituted Complex
HDAC10HSPA810954420032463 Affinity Capture-Western; Reconstituted Complex
HDAC10PAX311111120032463 Affinity Capture-Western; Reconstituted Complex
HDAC10PAX312381820032463 Affinity Capture-Western; Reconstituted Complex
HDAC10PPP1CC11149514670976 Co-purification
HDAC10PPP1CC12381814670976 Co-purification
HDAC10HDAC311436811861901 Affinity Capture-Western
HDAC10HDAC312381811861901 Affinity Capture-Western
HDAC10NCOR212381811739383 Affinity Capture-Western
HDAC10NCOR211497411739383 Affinity Capture-Western
HDAC10MDC112381814578343 Protein-peptide
HDAC10MDC111501414578343 Protein-peptide
HDAC10TRIM2811545720032463 Affinity Capture-Western; Reconstituted Complex
HDAC10TRIM2812381820032463 Affinity Capture-Western; Reconstituted Complex
HDAC10PAPOLA11611917172643 Affinity Capture-Western
HDAC10PAPOLA12381817172643 Affinity Capture-Western
HDAC10NUDT2112381817172643 Affinity Capture-Western
HDAC10NUDT2111623717172643 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
HDAC10rs1555048 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:2158340
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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